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JPM: Sanofi pays $125M to take lead in new checkpoint inhibitor space JPM: What does a virtual J.P. Morgan Healthcare Conference mean for the future of the meeting? Executives weigh in JPM: Boehringer inks Enara deal to source 'dark antigens' for cancer immunotherapies JPM: Novartis CMO Tsai on how the pandemic is changing the face of biopharma R&D, how pharma works Pfizer invests $120M in 4 biotechs through new growth fund Tessera Therapeutics scores $230M to ramp up 'gene writing' tech to cure disease JPM: Verve Therapeutics unveils its lead program—a one-and-done treatment for genetic high cholesterol Fierce JPM Week: Becoming a biotech CEO amid a global pandemic—a truly virtual biotech tale JPM: Illumina inks multiple cancer diagnostic partnerships to complement upcoming Grail acquisition Editor's Corner—8 things I won't miss about the Westin St. Francis as JPM goes virtual Novartis lays out $650M-plus for BeiGene's tislelizumab as its own PD-1 fails to impress JPM, Day 2: Sanofi continues deal spree, Boehringer shines light on dark antigens and more Featured Story | By Nick Paul Taylor Sanofi is paying Biond Biologics $125 million upfront for global rights to a novel immune checkpoint inhibitor. The agreement gives Sanofi a near-clinical anti-ILT2 monoclonal antibody designed to turn the innate and adaptive immune systems against tumors. read more |
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| Thank you to Catalent for sponsoring this year's JPM 2021 coverage. |
Top Stories By Amirah Al Idrus This year's virtual J.P. Morgan Healthcare Conference could be a "reset" that changes the trajectory of the meeting and its attendant events. Biopharma executives and their colleagues in communications and PR weighed in on what that means for 2021 and beyond. read more By Nick Paul Taylor Boehringer Ingelheim has partnered with Enara Bio to discover novel shared antigens for its growing cancer vaccine and bispecific activities. The agreement positions Boehringer to access novel “dark antigens” discovered by Enara. read more By Ben Adams This time last year, the life science world descended into San Francisco for the 2020 J. P. Morgan healthcare conference, doing the normal things like blowing a whole year’s budget in one day for a hotel room, shaking hands, doing deals and, if you’re like us, asking questions. read more By Nick Paul Taylor Pfizer has made the first investments through its $500 million Pfizer Breakthrough Growth Initiative (PBGI). Homology Medicines received the biggest piece of the first tranche of PBGI funding, landing $60 million to support its work on treatments for rare genetic diseases. read more By Amirah Al Idrus Move over, gene editing: There’s a new kid on the block. Tessera Therapeutics is pioneering “gene writing,” a kind of genetic medicine it hopes will surmount the limitations of gene editing and gene therapy—and investors have bet more than $230 million on the approach. read more By Amirah Al Idrus Verve Therapeutics debuted nearly two years ago with $58.5 million and a goal to bring one-and-done gene editing treatments to heart disease. Now, the company is marching toward the clinic with a treatment for a genetic form of high cholesterol. The treatment, VERVE-101, is a base editor, meaning it doesn’t cut DNA like CRISPR gene editing systems. read more By Ben Adams The story of a top pharma exec leaving the industry and delving into biotech has always been a fascinating one, but Olema’s new chief, Sean Bohen, M.D., Ph.D., took on the challenge amid the worst pandemic in more than a century. read more By Conor Hale Following its $8 billion pitch last year to acquire Grail and its upcoming multi-tumor blood test, Illumina is planning a deeper dive into cancer genomics with a slew of new biopharma development partnerships. read more By Carly Helfand As JPM goes virtual, there are a few things I definitely won’t miss—at all—about the experience, and most of them have to do with its longtime host venue, the Westin St. Francis. read more By Angus Liu Novartis is way late to the PD-1/L1 game, and, after its own project flunked a late-stage study, the Swiss pharma figures it needs an external candidate as belt and braces. So it picked BeiGene’s PD-1 inhibitor tislelizumab, previously partnered with cancer heavyweight Celgene until its merger with Opdivo developer Bristol Myers Squibb. read more By Ben Adams,Conor Hale Welcome to Day 2 of the annual J. P. Morgan healthcare conference. Here's your need to know, as Sanofi as it again with a second deal in as many days, Novartis talks about the positives of the pandemic on its processes and Boehringer turns to the dark side. read more Resources Sponsored By: Polpharma Biologics Innovative cell lines and early process development are critical to generate a high producing cell lines alongside a USP strategy to meet high quality standards. 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We invite you to learn more by reading Gene and Cell Therapy: A New Age of Medicine. Sponsored by: Catalent Autologous cell therapies have seen propelled growth since 2017, with the spotlight on the first FDA approval of a chimeric antigen receptor (CAR) T cell immunotherapy, Kymriah® (tisagenlecleucel), for the treatment of relapsed/refractory B-cell acute lymphoblastic leukemia. Sponsored by: Metabolon Learn six ways metabolomics provides greater confidence, higher success rates and complements the work of your in-house teams for your drug development pipeline. Sponsored by: Covance Download the whitepaper to learn how your safety organization can implement automation technologies to enable process and cost efficiencies, improve resource allocation and ensure compliance and quality. 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Learn how your company can cost-effectively empower its employees to be productive and secure while working remotely. Sponsored by: Catalent Learn about drug product process development challenges and risks, the difference between innovator and biosimilar drug product process development, and more during the drug product process development phase. Sponsored by: Catalent Learn about proven strategies for a successful product launch, including cross-functional team collaboration, risk management and using the right project management tools. Sponsored by: Catalent This eBook provides insights on key approaches and considerations for preparing your drug development program for long-term success. Sponsored by: Catalent In this webinar, pharmaceutical scientists present real-life examples of challenges they’ve overcome in the transfer of oral small molecules from a dedicated early-phase development site to a dedicated late-phase manufacturing site. Sponsored by: Outer Edge Technology Cybercriminals Are Actively Exploiting The Coronavirus Pandemic To Gain Entry To Enterprise Networks. Don’t Let Your Company Become The Next Ransomware Headline -- Make These Changes Now! Sponsored by: Catalent Get insights on key considerations for a successful tech transfer process for manufacturing a biologic drug product, including a case study on overcoming challenges in a process transfer for a sterile diluent. Sponsored by: Catalent In a BioPharma Dive industry survey, planning and forecasting were identified as top concerns for trial sponsors. In response to this need, the CSM team at Catalent has developed a methodology for identifying, evaluating, and proactively managing the inherent risks involved in clinical trial supply chain management. Sponsored by: Catalent Learn about a real-world example of how clinical supply management expertise was applied to overcome inventory challenges for a complex, global study. 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