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February 26, 2019

Today's Rundown

Featured Story

Compugen cuts 35% of workforce to push cash runway into mid-2020

Compugen is “streamlining” its R&D operations to pare down costs and ensure it can afford the phase 1 study of its lead asset, an anti-PVRIG antibody it is developing for various cancers.

Top Stories

Immunomedics could be facing longer lead drug delay as CEO quits

Immunomedics CEO Michael Pehl is heading for the exit as analysts at Jefferies suggest the delay to IMMU-132 for breast cancer could be longer than first expected.

Amicus plans to center its gene therapy R&D in Philadelphia with new lab

Amicus Therapeutics plans to build a gene therapy R&D center in the heart of Philadelphia’s University City, not long after inking a $100 million deal to acquire Celenex and its 10 gene therapies.

[Sponsored] Rise in Targeted Therapies Drives Need for Flexible, Small-Volume Manufacturing

Biologics have experienced steady double-digit growth over the last 15 years and now comprise slightly more than a quarter of all New Molecular Entity (NME) FDA approvals.

Syncona, Novartis back IL-2 immuno-oncology startup Anaveon

Syncona and Novartis have invested in Anaveon. The $35 million series A round sets Anaveon up to advance a preclinical asset designed to enhance anti-tumor immune responses.  

Purdue Pharma taps TetraGenetics for ion channel-focused pain treatments in $273M discovery pact

Purdue Pharma’s newly formed clinical research subsidiary, Imbrium Therapeutics, has tapped TetraGenetics and its antibody discovery platform to help it develop new, non-opioid-based biologics for treating chronic pain.

Notable Labs brings on 2 development executives ahead of its first blood cancer trials

After launching its first in-house R&D program last month, cancer drug-testing startup Notable Labs has brought on two biopharma executives to take charge of its clinical operations and drug development work.

Immatics, Roche ally to trial Tecentriq with cell therapy

Immatics has struck a deal to test its autologous cell therapy in combination with Roche’s checkpoint inhibitor Tecentriq. The clinical collaboration clears Immatics to test whether Roche’s antibody boosts the efficacy of its IMA101 in solid tumors.

Resources

[Whitepaper] Cell-Based Cancer Immunotherapies: Commercial Risk, Curative Reward

White paper outlining the key types of cell-based immunotherapies in oncology, as well as the development and commercial outlook for each.

[Whitepaper] Better Market Intelligence With Smart Search

It’s never been more challenging to stay on top of trends and innovation shaping the future of healthcare. Discover how AI can help competitive intelligence teams achieve more proactive strategies.

[Whitepaper] Managing Demand Uncertainty in Biologics Production

When a biologics company prepares to launch a new product, it must forecast the manufacturing capacity it will need, factoring in its estimate of the size of future sales, the timing of the launch, the dosage of the product, its strategy for building its market and a host of other variables.

[Whitepaper] RTSM/IRT: A Roadmap For Developing Systems That Address Current Frustrations

92% of survey respondents make changes to their RTSM/IRT systems due to study changes. See what else puts a strain on their clinical trials. Download the Research Whitepaper.

[Whitepaper] Six API Challenges That could be Slowing your Development

Download this whitepaper to learn more.

[Whitepaper] Engaging Organized Customers in the Era of the Quadruple Aim

Explore how the pharma industry can adapt its approach to the changing healthcare marketplace in the era of the Quadruple Aim

[Whitepaper] Clinical Validation of a Powerful Immune Assay for Patient Selection

Learn how Health Expression Models provide increased sensitivity, specificity, and accuracy for characterizing immune response in solid tumor specimens.

[Whitepaper] Host Cell Protein Analysis in Biologic Drug Development

This whitepaper reviews fundamental aspects of HCPs that pertain to biologic drug development and presents current and emerging approaches to HCP analysis.

[Whitepaper] Integrating clinical research at the Point of Care—A New Operating Model

Clinical trials take too long and cost too much—here's what needs to change.

[Whitepaper] Accelerate Time To Market Working With Industry Specialist MSP

With FDA approval imminent, start-up Life Sciences company partners with an industry focused MSP to design and manage its regulated cloud-based infrastructure to speed time to market.

[Survey] Veeva 2019 Unified Clinical Operations Survey

Share your thoughts on the life sciences industry's progress in improving study execution.

[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

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