Novavax links vaccine to full protection against severe COVID-19 caused by emerging variants Sanofi, hit by COVID vaccine setback, kickstarts mRNA trial with Translate Bio Prometheus upsizes IPO, fueling chase of Pfizer in bowel disease Monte Rosa snags $95M to speed lead ‘molecular glue’ treatment into the clinic Mitochondrial biotech Minovia Therapeutics nabs biopharma veteran Alan Jacobs as new chief medical officer UCSD spinout pursues gene therapy for chronic pain following positive data in mice Fierce Pharma Asia—Takeda's Maverick buyout; Brii COVID antibodies' trial halt; Dr. Reddy's generic Lipitor recall Chutes & Ladders—Lilly taps new manufacturing lead as longtime chief O'Neill tees up retirement Featured Story | By Nick Paul Taylor Novavax has linked its COVID-19 vaccine to 100% efficacy against severe disease in countries where variants of concern are prevalent. The final phase 3 data suggest NVX-CoV2373 may protect against the worst outcomes caused by the coronavirus variants, even though the mutations limit its efficacy. read more |
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Top Stories By Ben Adams Sanofi doubled down on its original 2018 pact with Translate Bio last year as the pair teamed up for an mRNA approach to COVID vaccines, and today the two announced they are starting clinical trials using the tech. read more By Nick Paul Taylor Prometheus Biosciences has upsized its IPO, positioning it to reel in $190 million to bankroll clinical development of an anti-TL1A monoclonal antibody in inflammatory bowel disease (IBD). read more By Amirah Al Idrus Monte Rosa is at it again, banking $95 million just six months after reeling in a $96 million series B. The funds will propel the company’s lead protein-degrading program into the clinic, while ramping up pipeline growth and boosting its drug discovery and development platform. read more By Ben Adams As it awaits FDA feedback on its pivotal trial for its leading med, Minovia Therapeutics has hired Alan Jacobs, MSEE, M.D., Ph. D to help boost it over the line. read more By Angus Liu Scientists at UCSD successfully used CRISPR and zinc finger gene-editing tools to suppress a pain-related ion channel protein called NaV1.7 in spinal neurons. Both approaches led to durable pain relief in mice. Startup Navega Therapeutics aims to launch a clinical trial in the next few years. read more By Angus Liu Takeda turns partner Maverick Therapeutics into a buyout target. Brii Biosciences' COVID antibody cocktail became the latest to fail in hospitalized patients. Dr. Reddy's recalls a large volume of generic Lipitor in the U.S. due to impurities. And more. read more By Fraiser Kansteiner Lilly's longtime manufacturing chief is retiring in May, to be replaced by company veteran Edgardo Hernandez. Slaoui's Centessa Pharmaceuticals tapped a new CFO and added three members to its board of directors. Plus, immune regulation biotech Q32 has a new CMO. read more Enrollment Showcase | Sponsored by: University of Florida College of Pharmacy Learn about the Top 5-Ranked UF College of Pharmacy’s online graduate programs in pharmaceutical outcomes & policy. Select from five specializations, including the new pharmaceutical value assessment & communication option. Over half of graduates progress to a new role within one year. Register now. |
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