Vincerx to wind down after merger collapses

Today’s Big News

Apr 9, 2025

From ADCs to radiopharma: How AstraZeneca is trying to ‘redefine oncology care’


HHS cuts contract spend by 35%, with 334 pacts already terminated


Vincerx's final merger attempt collapses, leaving ADC biotech to wind down


Judge permanently blocks NIH grant caps, prompting HHS appeal


Former CBER head Peter Marks says he blocked RFK Jr. from vaccine safety database before leaving FDA: AP


Cornell and Northwestern next up for federal funding freeze, jeopardizing health research


NIH blocks researchers in China, Russia and other countries from multiple databases


Vaccine-probiotic combo prevents, clears bacterial gut infections in mice in antibiotic alternative test

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Featured

From ADCs to radiopharma: How AstraZeneca is trying to ‘redefine oncology care’

AstraZeneca has been busy in recent years picking up a shopping list of assets and companies that have pumped up its oncology pipeline.
 

Top Stories

HHS cuts contract spend by 35%, with 334 pacts already terminated

In the latest of a string of clawbacks, the Department of Health and Human Services is now sharing plans to cut contract spending by 35% across all divisions.

Vincerx's final merger attempt collapses, leaving ADC biotech to wind down

With two attempts to merge with other companies having collapsed, Vincerx Pharma has been left with no choice but to start winding down.

Project Optimus: Transforming Dose Optimization in Oncology Drug Development

Project Optimus is changing the landscape of oncology drug development by redefining dose optimization standards. Learn how sponsors can align with FDA expectations and implement more precise dose-finding strategies. Watch the full interview with Alex MacDonald now!

Judge permanently blocks NIH grant caps, prompting HHS appeal

On Monday, a federal judge permanently blocked the National Institutes of Health from implementing indirect cost caps on research grants. The NIH is now appealing.

Former CBER head Peter Marks says he blocked RFK Jr. from vaccine safety database before leaving FDA: AP

Peter Marks, M.D., Ph.D., the former director of the Center for Biologics Evaluation and Research, told the Associated Press that he blocked HHS secretary Robert F. Kennedy, Jr. from securing full access to the Vaccine Adverse Events Reports System in the fear that the secretary's team would erase the database.

Cornell and Northwestern next up for federal funding freeze, jeopardizing health research

The Trump administration’s effort to slash federal funding to universities has found its latest targets, with the government reportedly freezing $1 billion in funds to Cornell University and $790 million to Northwestern University.

NIH blocks researchers in China, Russia and other countries from multiple databases

The Trump administration has blocked access to multiple data repositories maintained by the National Institutes of Health for researchers in several countries, including a cancer statistics database used regularly by scientists in China.

Vaccine-probiotic combo prevents, clears bacterial gut infections in mice in antibiotic alternative test

Researchers combined a vaccine and a probiotic supplement to tend the microbial garden inside the intestines of mice, protecting the rodents from harmful infections or treating them if they’ve already caught a nasty bug as scientists continue to seek a future alternative to antibiotics.

Worldwide Clinical Trials turns to AI company to identify hidden patient subpopulations in big data sets

Global CRO Worldwide Clinical Trials has enlisted AI tech firm NetraMark to discover patient subpopulations hidden inside complex data sets.

Stroke tech developers Kandu, Neurolutions combine with $30M in new funding

The revamped Kandu will move forward with $30 million in new financing, through a round co-led by Ally Bridge Group and Amed Ventures.

Vertex CEO Reshma Kewalramani gets 4% pay bump to $21.5M

After another solid year that included 12% growth in the top line, Vertex has bumped up its compensation for CEO Reshma Kewalramani, M.D., to $21.5 million, according to the company’s proxy filing.
 
Fierce podcasts

Don’t miss an episode

A closer look at pharma's top R&D budgets

This week on "The Top Line," we dive into our special report ranking the top pharma R&D budgets for 2024.
 

Resources

Unlocking Genomic Data: How NashBio is Advancing Innovation in Life Sciences

NashBio is transforming life sciences by making complex genomic and real-world data accessible for pharmaceutical R&D. Learn how their innovative Totem platform and groundbreaking Alliance for Genomic Discovery are accelerating research and improving outcomes.

eBook

Through a CRO's perspective: Innovative, Agile Solutions In Vaccine Efficacy Testing

Typical vaccine development timelines have averaged 10 years, but the time from the SARS-CoV-2 genetic sequence’s release to the submission of the first vaccine clinical trial data for regulatory review was a mere 314 days. In IQVIA Laboratories’ Vaccine eBook we focus on how contract research organizations (CROs) can best leverage strategic partnerships with sponsors to prepare for the next pandemic.
Whitepaper

Protect Your Trial Data: Endpoint, Imaging, and Safety Review

Avoid costly mistakes and ensure your clinical development program meets the highest standards by reading WCG’s whitepaper on Imaging Core Labs, Endpoint Adjudication Committees (EAC), and other safety reviews.
Research

Best Practice Customer-Facing Organization Study Report

We interviewed 15 biopharma leaders on the critical success factors for building a Best Practice customer-facing organization. This report shares what we learned.

 

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