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June 04, 2019___

Today's Rundown

Featured Story

In a much-needed positive for BMS, Celgene gains FDA review for blockbuster hopeful

The $74 billion deal that will see Bristol-Myers Squibb subsume Celgene into its ranks is all but done, but it’s been a rocky path. Today, Celgene delivered some positive optics for its would-be parent.

Thank you to Lonza for sponsoring this week's coverage of BIO.

Top Stories

ASCO: AstraZeneca's Baselga on tailoring treatments and the march to cure cancer

José Baselga, AstraZeneca's R&D chief, sat down with FierceBiotech to talk capivasertib data, how to pick the best drug for each patient and what needs to change before cancer is cured.

Woodford suspends trading in flagship fund after investors flee

Neil Woodford has suspended trading in his flagship fund after investors withdrew £10 million a day last month. The surge in outflows follows sustained poor performance by the fund that culminated in it being among the worst performers in May.

[Sponsored] How to Make the Most of Your Clinical Trial Data—All of it

Pharma and biopharma have endless data at their disposal. Why aren't they using it? Here's how to make the most of your data for clinical success.

Jazz Pharma nabs Immunomedics' Iannone as R&D chief

Just over a month after walking out on troubled cancer biotech Immunomedics, Robert Iannone, M.D., has taken up the research chief job at Jazz Pharmaceuticals.

Bayer inks Arvinas deal to develop protein degraders

Bayer is paying Arvinas $17.5 million upfront to develop protein-degrading treatments for cardiovascular, oncological and gynecological diseases. The partners will apply Arvinas’ targeted protein degrader technology to targets selected by Bayer.

Hoping to win where Novartis failed, Inhibrx files for $75M IPO

Inhibrx has filed for a $75 million IPO. The Celgene-partnered single-domain antibody specialist will use the money to complete phase 1 trials of three drugs targeting cancers and rare diseases.

ASCO: Viracta's HDAC-inhibitor combination garners high response in EBV-linked lymphoma

In an early trial, 58% of patients with lymphoma that's associated with Epstein-Barr virus (EBV) responded to a combination of Viracta Therapeutics’ HDAC inhibitor nanatinostat and an antiviral drug. The company is now planning a phase 2 study of the combo.

Massive Bio, IBM Watson, others team up with Biden Cancer Initiative for oncology work

Trial "matchmaker" Massive Bio, IBM Watson and a host of other organizations have partnered with former Vice President Joe Biden’s Cancer Initiative to help improve patients’ access to and the work coming from cancer studies.

AstraZeneca scouts replacements for longtime chairman Johansson: report

AstraZeneca's Leif Johansson has put in seven years as chairman, through some big ups and downs—including Pfizer's hostile takeover attempt. Now, the company's starting to scout for a potential successor, Sky News reports.

Resources

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[Report] Precision medicine from concept to clinic

In this publication, Blue Latitude Health maps the journey of stakeholders impacted by the rise of precision medicine today. Download the report.

[Whitepaper] Flow Chemistry: A Scale-Up Solution for Modern API Development & Manufacturing

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[On-Demand Webinar] Lessons Learned Implementing an End-to-End RIM Solution

IONIS shares best practices for implementing an end-to-end RIM solution in this on-demand webinar. Watch now.

[Whitepaper] Site-specific, Patient-centered and Whip-smart: Enrollment Assistants Adapt to a Shifting Landscape

Increasingly complex clinical trials place a tremendous burden on study sites, exacerbating already-troubling recruitment and enrollment issues. Overwhelmed, many sites may not be up to the task or have the appropriate infrastructure, creating costly delays that keep new therapies from patients.

[Case Study] Clinical Supply Management

Download the case study to learn about the clinical supply management tools that helped a small sized pharma company during phase III of a multi-arm oncology study.

[Video] Demand Led Services and Clinical Supply Efficiency

Watch a short video on demand led supply model. It is designed to meet the needs of patients, clinical sites, clinical team and sponsors and results in shorter lead time, less waste, less stock out risk and no booklet labels.

[eBook] Strategies for Efficient Clinical Supply Management and Forecasting

Download the eBook to explore a proactive approach for clinical supply management.

[Executive Summary] Achieving a Successful Drug Product Tech Transfer

Download the executive summary to learn key considerations for a successful technology transfer for manufacturing drug products, including a case study on overcoming challenges in a process transfer for a sterile diluent.

[Whitepaper] Choosing the Best Sterile Dosage Form for Phase I Clinical Supply Needs

Choosing the Best Sterile Dosage Form for Your Phase I Clinical Supply Needs.

[Whitepaper] Delivering oral solid dose product to Phase I Clinic in 14 weeks

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