AI biotech bags $372M megaround

Today’s Big News

Jun 26, 2024

CAR-T death drives Lyell to take 2-track approach to dose escalation


Alexis Borisy-founded VC raises $380M for early-stage biotechs


AI-focused Formation secures Sanofi-backed $372M series D to license more drugs


Arrowhead axes heart disease drug, goes all in on another as pipeline progress drives costs up


Intellia doesn't need to re-dose gene edited NTLA-2001. But new data shows it can be done


GSK, Moderna, Novartis and more join Slope in new biospecimen consortium

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Featured

CAR-T death drives Lyell to take 2-track approach to dose escalation

A death and other adverse events have forced Lyell Immunopharma to take a two-track approach to its early-phase CAR-T clinical trial, holding back dose escalation in people with lung metastases while racing ahead in the wider population.
 

Top Stories

Alexis Borisy-founded VC raises $380M for early-stage biotechs

Venture capital firm Curie.Bio has fueled up, raising $380 million for biotech founders and promising to stretch the runway of seed money for better long-term results.     

AI-focused Formation secures Sanofi-backed $372M series D to license more drugs

Megarounds have been few and far between in 2024, but Formation Bio has managed to draw in an impressive $372 million series D as the AI-focused biotech seeks to expand its pipeline.

Why early market access planning is crucial in CGT commercial strategy

CGT companies should consider developing a market access strategy early in clinical development, ideally more than three years prior to launch.

Arrowhead axes heart disease drug, goes all in on another as pipeline progress drives costs up

With two cardiovascular disease candidates in or near phase 3, RNAi specialist Arrowhead Pharmaceuticals has dropped one prospect and thrown its weight behind the other to manage its spending.

Intellia doesn't need to re-dose gene edited NTLA-2001. But new data shows it can be done

Intellia Therapeutics doesn’t need to redose patients with a CRISPR gene edited therapy for transthyretin (ATTR) amyloidosis. But new data suggests it could be done.

GSK, Moderna, Novartis and more join Slope in new biospecimen consortium

The Biospecimen Management Consortium will see major players in Big Pharma aim to establish best practices for handling patients’ biological samples, or biospecimen, during clinical trials.

DNA testmaker BillionToOne claims billion-dollar valuation with $130M funding round

BillionToOne said the proceeds will help scale up its blood testing businesses in prenatal screening and cancer.

After IBD wins, J&J's Tremfya misses the mark in giant cell arteritis

As other immunology players make inroads into the giant cell arteritis arena, one of Johnson & Johnson’s top-grossing medicines, Tremfya, has come up short in the disease.

Arkansas files opioid epidemic lawsuit against PBMs Optum, Express Scripts

Arkansas says Optum and Express Scripts have not adequately protected consumers from the dangers of opioids, instead using their profits to grow into vertically integrated giants.
 
Fierce podcasts

Don’t miss an episode

A closer look at 'friend-shoring' and the drug shortage challenge

In this week’s episode of “The Top Line,” Fierce Pharma’s Zoey Becker sits down with Bobby Sheng, the CEO of Bora Pharmaceuticals, to discuss the concept of “friend-shoring” in drug manufacturing.
 

Resources

Whitepaper

2024 Life Sciences Industry Outlook

The definitive report on the state of our industry.  Readers will gain an understanding of key indicators to monitor, future predictions, and guidance for investors and founders navigating the therapeutic enabling tools and services, healthtech and techbio sectors through 2024 and beyond.
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Enhance your long-term cell & gene therapy success with pDNA manufacturing solutions

Watch our on-demand webinar video to learn more about the challenges in pDNA manufacturing for gene and cell therapy and how to resolve many of these barriers by partnering with our experts through the adoption of vital manufacturing technologies and strategies.
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A Comprehensive and Flexible Approach to CMC for Fab and Fc-Fusion Development Programs

New molecular formats are gaining momentum in today’s market. Characterizing these products and developing robust manufacturing processes can help to usher them to market and provide new treatment options for diseases which are currently challenging to treat. Read this white paper to learn more.
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Fresenius Medical Care gets 25x faster kidney disease insights

This detailed case study shows how Fresenius Medical Care achieved 25 times faster insights to help kidney disease patients, launching the world’s largest global database of dialysis care with fully anonymized patient data.
Whitepaper

Adding Rare Disease Products to Your Company’s Portfolio

This paper outlines the challenges, pitfalls, & solutions associated with adding rare disease therapies to a biopharma company’s portfolio.
 

Industry Events

On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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