IRA may hit R&D harder than expected, study finds

Today’s Big News

Sep 6, 2023

J&J hands back $230M blood pressure drug to Idorsia with approval in sight


Janssen sticks with Cidara’s flu med, but intends to hand over rights to someone else 


Gilead-backed study warns IRA price negotiations could hit R&D harder than expected


Apollo lands $226M series C for mysterious pipeline spread across hub-and-spoke R&D model 


Nimbus tacks on $210M in funding as investors swat away IRA concerns


Kriya continues acquisition streak, snapping up gene therapy biotech and diving into the NASH space


Moderna, hoping for swift approval, shows updated COVID shot can defend against pirola variant


Umoja's in vivo CAR-T therapy shows positive first signs in primates

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Featured

J&J hands back $230M blood pressure drug to Idorsia with approval in sight

Johnson & Johnson is backing away from its $230 million blood pressure bet, returning the global rights to the near-approval treatment to Idorsia in a deal worth up to $343 million.
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Top Stories

Janssen sticks with Cidara's flu med but intends to hand over the rights to someone else

Janssen has elected to stick with a 2021 deal for Cidara's flu prophylaxis but will likely hand over the rights to someone else. Cidara earned a $7 million milestone payment thanks to the decision and still stands to earn more than $650 million in potential biobucks.

Gilead-backed study warns IRA price negotiations could hit R&D harder than expected

How hard will the Inflation Reduction Act hit pharma R&D? Harder than the government expected, according to work by the University of Chicago that found lower R&D spending could result in 79 fewer new small-molecule drugs over the next 20 years.

Apollo lands $226M series C for mysterious pipeline spread across hub-and-spoke R&D model

Apollo Therapeutics is launching its series C flight with $226.5 million, money that will bolster its hub-and-spoke approach to drug development and 20-plus pipeline programs that remain largely under wraps.  

Nimbus tacks on $210M in funding as investors swat away IRA concerns

Nimbus Therapeutics has tacked on an additional $210 million in private capital, pushing the company's total fundraising haul since inception past $600 million. CEO Jeb Keiper says the company has no intention to go public as of now.

Kriya continues acquisition streak, snapping up gene therapy biotech and diving into the NASH space

While it’s been a rocky year for many, everything is smooth sailing at Kriya Therapeutics—one of biotech’s top money raisers last year—as it continues its acquisition streak. This time, Kriya has snapped up Tramontane Therapeutics and will be developing a NASH program sourced from the gene therapy biotech.

Moderna, hoping for swift approval, shows updated COVID shot can defend against pirola variant

Moderna is continuing to make the case for why its updated COVID-19 shot needs a speedy approval in time for the fall vaccination season, now pointing to its effectiveness against the so-called pirola variant.

Umoja's in vivo CAR-T therapy shows positive first signs in primates

The company's VivoVec platform has generated in vivo chimeric antigen receptor T cells, or CAR-T cells, in nonhuman primates, according to new data presented by the company Sept. 1 during the annual CAR-TCR Summit in Boston. The CAR-Ts also appeared to have activity against target cells and continued proliferating for more than a month in one of the animals.

Novartis cuts top commercial title, replaces departing exec Marie-France Tschudin with AbbVie vet Patrick Horber

Just as Novartis’ C-suite appeared to have stabilized amid a major overhaul of the company, the Swiss pharma is losing its international markets leader and getting rid of its chief commercial officer title.

Blue Cross NC removes HIV drugs from costly price tiers

A lawsuit against Blue Cross and Blue Shield of North Carolina appears to have prompted the insurer to backtrack and remove 48 HIV drugs from its costliest drug tiers.

Abbott tracks down Bigfoot Biomedical in deal to combine diabetes tech

It’s no legend: Abbott has captured Bigfoot Biomedical by striking a deal to acquire the diabetes management tech maker.

CMS unveils new model aimed at chronic disease

Based on care models out of Maryland, Vermont and Pennsylvania, CMS is implementing the AHEAD Model to help states address chronic disease.
 

Resources

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A New Era of Collaboration for Life Sciences

Access this insightful whitepaper to explore the role collaboration platform technology can play in helping address current industry challenges and to generate business value.

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What Are the Benefits of Generative AI for Pharma?

From trial site feasibility and patient populations to data analysis, generative AI has the potential to revolutionize drug discovery and clinical trial recruitment at both the therapeutic area and indication level.
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Discovering High-Affinity, Functional Anti-GLP-1R Antibodies

Learn how a GPCR-focused library with a cell-based biopanning strategy led to the discovery of 13 high-affinity and selective anti-GLP-1R antibodies with highly developable therapeutic properties.

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Five ways to get the most from your lab and manufacturing facilities

Learn more about how you can improve the productivity of your research and manufacturing operations and accelerate the journey from laboratory to saving lives.

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Transitioning from using RUO to cGMP chemicals for clinical trials

By 2030, the global demand for biologics is projected to grow at a CAGR of 8.7% and the challenges, risks, and costs of bringing large molecule products to market are growing exponentially.

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Biotech in the UK: Mapping the Runway to Success

15 biotech executives from the Cambridge area discuss the current biotech landscape, as well as challenges, opportunities, and best practices for emerging biotech companies seeking success in the UK and beyond.
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Plan for success with your process liquid and buffer preparation

Learn how process liquids and buffers impact your total cost of ownership (TCO) and how outsourcing can revolutionize your approach, ensuring quality standards and improving productivity.
 

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