To view this email as a web page, click here

   Home

Subscribe

Advertise

 

 

 

 

September 19, 2019___

Today's Rundown

Featured Story

Ginkgo raises $290M to fuel synthetic biology expansion

Ginkgo Bioworks has raised $290 million. The synthetic biology unicorn will use the series E funds to continue building on a cell programming platform it thinks can upend multiple industries.

Top Stories

IPO take 2: Kindler's Centrexion restarts bid to fund pain trial

Centrexion Therapeutics has restarted its attempt to list on the Nasdaq. The Jeff Kindler-helmed biotech pulled the plug on a planned IPO last year but now hopes to find investors more amenable to its bid to raise money for a phase 3 pain program.

Could a combo treatment boost KRAS inhibitors in lung cancer?

KRAS made a splash at this year’s ASCO after Amgen’s early data for first-to-clinic inhibitor AMG 510 triggered blockbuster chatter. Now one research team has early evidence that the combo could further increase KRAS inhibitors’ therapeutic effects in lung cancer.

[Sponsored] Solutions to Today’s Biomanufacturing Challenges

With more complex molecules in development, changing capacity needs, uncertain forecasts and increased competition, the market demands flexibility and innovative approaches to address these challenges.

Medicxi founds biotech to Divide & Conquer tough solid tumors

Moncef Slaoui and his colleagues at Medicxi have taken the wraps off a new oncology startup, Divide & Conquer. The biotech wants to interrupt the cell-to-cell communication that may make some solid tumors hard to treat.

Boundless Bio uncloaks with $46M to create new cancer drugs aimed at extrachromosomal DNA

Boundless Bio was founded on a discovery that a group of cancer-driving mutations called amplifications occur in extrachromosomal DNA, or DNA that resides outside of the chromosome in cancer cells.

Spruce scores phase 2a win for rare disease drug, gears up for 2020

New phase 2a data show Spruce's lead drug reduced the level of three hormones overproduced by patients with congenital adrenal hyperplasia, teeing it up for its next trial slated to start in 2020.

Black Diamond grabs trio of new R&D execs as it barrels toward the clinic

After a whirlwind year and two quick-fire raises, cancer startup Black Diamond Therapeutics has nabbed Yumanity, Merck KGaA and SR One veterans to help head up its research work.

Success of nearly half of European cancer drug trials 'exaggerated' due to bias: report

Trials for cancer drugs undertaken in Europe in the mid-2010s were flawed to such a degree as to “raise questions” over their true benefit to patients, according to a new report out this week from British science journal The BMJ.

DeepMind's health team makes the jump to Google with some NHS partnerships in tow

About 10 months after first announcing the move, Google has subsumed the healthcare-focused efforts of U.K.-based artificial intelligence firm DeepMind—and with them, its data-sharing partnerships with multiple National Health Service hospitals.

Zolgensma trial death unrelated to gene therapy, Novartis says, touting new data

Novartis unveiled new long-term Zolgensma data that could dispel worries spawned by last month's data manipulation scandal. And at the same time, it put out news to clear up concern that a trial patient's death was related to Zolgensma treatment.

Enrollment Showcase

BioImmersion: Biotech for the Non-Scientist

BioImmersion: Biotech for the Non-Scientist is a three-day, in-depth course that delves into the scientific details on a broad number of biotechnology topics. Register today!

Resources

[Whitepaper] Fail Fast. Succeed Faster.

Slashing your R&D costs is easier than you think.

[Whitepaper] Innovative Funding Models for Treatment of Cancer and Other High-Cost Chronic Noncommunicable Diseases

A global landscape study of funding trends and innovations.

[Whitepaper] Advanced Analytical Approaches for Accelerated Development of Gene Therapy Products

Download the White Paper and learn how detailed characterization can guide successful development of gene therapy products.

[Whitepaper] Understanding Precision Medicine in Oncology

White paper providing an overview of precision medicine in oncology, as well as a look ahead at future developments and keys to success for pharmaceutical and diagnostics companies.

[Whitepaper] How Can You Avoid the Fallout From Incompatibility Between Your API and Its Formulation?

Avoid potential risks to the patient as well as costly interruptions during development.

[Article] Why Market Leaders Outsource IT Requirements For A Competitive Edge

Find out how outsourcing your IT requirements enhances the bottom line while creating strategic advantage.

[Whitepaper] From Complex to Controlled: Advanced Data Management Strategies for Advanced Therapies

Developing a cell therapy, gene therapy, or personalized cancer vaccine? Modern data management makes a critical difference in operational and regulatory outcomes. This whitepaper will help your team leverage the latest data strategies for success.

[Whitepaper] Advancing Healthcare Market Intelligence With Smart Search Technology

AI-powered research tools are making it easier to source confident healthcare market intelligence with accuracy and efficiency -- download now to learn more about improving your competitive research strategy.

[Whitepaper] What's Your Lab Trying to Tell You? Listen with Connected IoT Sensors

Your lab is talking to you, are you listening?

[Whitepaper] Prevent the Real World From Derailing Your Clinical Trial: Focus on Protocol Design

Want to be sure your renal research protocol design is fit for the real world?

[Whitepaper] Optimizing Operations in Multiproduct Pharma Manufacturing Facilities

Vetting CDMOs but unsure what to look for in prospective partners’ multiproduct facilities?

[Report] Future of clinical trials: From real-time data to algorithmic trials

Clinical trials are one of the pharma industry’s most painful and costly processes. Read how technology could transform the trial process from nine years to a matter of hours.

[Whitepaper] Considerations and Options for Prefilled Syringes

Check out Baxter BioPharma Solutions’ whitepaper to learn considerations and options for developing a product in a prefilled syringe.

[Article] Sales Compensation: 7 Trending Topics

From sales headcount and budgets to new product launches and saying “yes” to millennials, hear the top 7 topics that are trending in sales compensation.

[Whitepaper] The Supply Chain Planning Cure for Everything from Product Expirations to Patent Cliffs

Download this life sciences industry spotlight to discover how concurrent planning can help you overcome complex supply chain challenges to drive down costs and improve efficiency.

[Case Study] Clinical Supply Management

Download the case study to learn about the clinical supply management tools that helped a small sized pharma company during phase III of a multi-arm oncology study.

[Video] Demand Led Services and Clinical Supply Efficiency

Watch a short video on demand led supply model. It is designed to meet the needs of patients, clinical sites, clinical team and sponsors and results in shorter lead time, less waste, less stock out risk and no booklet labels.

[eBook] Strategies for Efficient Clinical Supply Management and Forecasting

Download the eBook to explore a proactive approach for clinical supply management.

Events