By 2025, AbbVie’s industry-leading Humira is expected to sail off the patent cliff and fall to No. 6 in the rankings, while others aim to take its place. That includes Merck’s Keytruda, which GlobalData forecasts will take the crown with $22.5 billion in sales—outpacing not only Bristol-Myers Squibb and Pfizer’s Eliquis and Celgene’s Revlimid, but also BMS’ Opdivo and AbbVie and J&J’s Imbruvica as well. But meanwhile, BMS is working to complete its merger with Celgene, which will give it three of 2025’s top four drugs, totaling over $43 billion. Read on below. | |
| Featured Story | Friday, October 4, 2019 AbbVie's Humira has been topping pharma's sales charts, but in a few years it'll be passed by Merck's Keytruda and several other meds, a GlobalData forecast shows. Also in the top 10 are Bristol and Pfizer's Eliquis, Celgene's Revlimid, and BMS' Opdivo. |
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| Top Stories Of The Week Monday, October 7, 2019 After a series of major exits from its C-suite last year and this year including the exit of Chief Medical Officer Andrew Cheng last fall, Gilead now has a new CMO as it also rejigs its R&D reporting line. Wednesday, October 9, 2019 Merck & Co. and Pfizer are in a very public race to market with their next-gen pneumococcal vaccines. But behind the scenes, Merck claims a former high-level employee jumped ship to Pfizer with a load of trade secrets, giving its rival an unfair advantage. Monday, October 7, 2019 After an unexpected game of executive musical chairs, Akcea Therapeutics has inked a deal with a potential rival. For $250 million upfront, Akcea is licensing an antisense therapy to Pfizer for “certain cardiovascular and metabolic diseases.” Thursday, October 3, 2019 Before Donald Trump became U.S. president, he warned pharma he’d be the one to crack down on the industry. Now, as Democrats advance an impeachment inquiry, he said it wouldn't surprise him if pharma companies were behind the effort. Monday, October 7, 2019 Researchers who advanced understanding of how cells sense and adapt to oxygen availability have won the 2019 Nobel Prize in physiology or medicine. The research could inform development of treatments for diseases including anemia, cancer and stroke. Tuesday, October 8, 2019 Novartis has its next big drug approval. The FDA on Tuesday approved wet AMD drug Beovu, which will go up against entrenched blockbusters Eylea from Regeneron and Lucentis from Roche. The drug has shown it can match up against Eylea's efficacy and bested the Regeneron drug on other measures. Friday, October 4, 2019 Zombie biotech Dynavax will lose its chief scientific officer in December, but after a host of cuts, it won’t be looking for a new one. Friday, October 4, 2019 Physicians are seeing fewer pharma sales reps than ever, which likely isn’t a surprise. But what might raise some eyebrows is the fact that digital contact by reps isn’t taking up the slack. Instead, doctors are searching for drug and treatment information online and on their own. Tuesday, October 8, 2019 Illumina and Qiagen signed on to a long-term diagnostics partnership—with the latter opting to develop kits for the sequencing giant’s hardware, rather than continuing to develop its own instruments. The two companies plan to work together on a series of next-generation sequencing-based tests in different therapeutic areas over the next 15 years. Monday, October 7, 2019 Johnson & Johnson's Janssen has had biopharma operations in Ringaskiddy, Co. Cork for nearly 15 years. Now it has a new $350 million facility there and added 200 jobs. Monday, October 7, 2019 A drug from Boston Pharmaceuticals called BOS172722 causes cancer cells to divide too rapidly and die. 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