| | By Kevin Dunleavy In the biopharma industry, post-merger layoffs are often a question of when and how many. In the case of Amgen’s $27.8 billion buyout of Horizon, they came quickly. Around 350 former Horizon employees are being told this week that their positions will be eliminated. |
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By Nick Paul Taylor One of the last drugs standing at Johnson & Johnson’s slimmed-down infectious disease unit has come through another test. The oral candidate, JNJ-1802, induced antiviral activity against dengue in a human challenge study, offering J&J encouragement as it works toward data in a larger community-based trial. |
By Nick Paul Taylor Merck & Co. has secured a seat at the productive Daiichi Sankyo antibody-drug conjugate (ADC) factory. While AstraZeneca picked up the first two ADCs off the production line, its rival and collaborator Merck is paying $4 billion upfront to co-develop Daiichi’s next three prospects. |
By Annalee Armstrong MADRID—Moderna and BioNTech have quite a few things in common, one being that both are trying to chart their post-COVID course by reinventing cancer modalities. And both, it seems, have run into the reality of manufacturing challenges. |
By Angus Liu Last year, a first-of-its-kind head-to-head clinical trial between two PD-1 inhibitors went in GSK’s favor. Now, the British pharma has some new patient survival data to celebrate. |
By Angus Liu As Novartis aims to move its radiotherapy Pluvicto into an earlier treatment setting in prostate cancer, it has posted a mixed bag of trial data that cast a cloud of uncertainty over its regulatory path forward. |
By Annalee Armstrong BioNTech’s new manufacturing process for CAR-T seems to have done the trick in boosting the potency of the solid tumor therapy BNT211, but that bit of extra juice seems to have upped the side effect profile as well. |
By Annalee Armstrong If anyone in Spain is wondering where the espresso machines are, they are at the exhibit hall for the European Society for Medical Oncology Congress, where one faces an important question: From which Big Pharma will I accept my complimentary espresso beverage? |
By Andrea Park After spending the better part of the last three decades at Johnson & Johnson, Ashley McEvoy, worldwide chair of its medtech franchises, is charting a new course. |
By Helen Floersh A vaccine designed to target three different strains of potentially lethal coronaviruses, including the one that causes COVID-19, appears to be effective in mice. |
Fierce podcasts Don’t miss an episode |
| In this week's episode of “Podnosis,” we look at the major health disparities facing Native Americans and explore what can be done to make meaningful improvements. |
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