Gilead stops 3 filgotinib trials pending FDA feedback on faltering JAK1 inhibitor Regeneron's COVID-19 antibody cuts medical visits in phase 2/3 trial Cancer combos are king as Sanofi-Merck and AstraZeneca-Arcus team up for next-gen trials Novartis sharpens focus on vision-restoring gene therapy with $150M Vedere buyout Q32 Bio banks $60M as it ramps up 'immune rebalancing' programs LianBio nets $310M to bring medicines to Asia Syneos Health snaps up late-stage CRO Synteract, aims to 'drive growth' among emerging biopharmas Takeda digital transformation continues with trial data platform pact through Seqster Featured Story | By Nick Paul Taylor Gilead has paused enrollment in clinical trials of filgotinib in three indications pending feedback from the FDA. The cessation of enrollment follows the FDA’s decision to reject a filing for approval of the JAK1 inhibitor in rheumatoid arthritis due to toxicity concerns. read more |
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Top Stories By Nick Paul Taylor Regeneron’s anti-SARS-CoV-2 antibody cocktail has significantly reduced medical visits in ambulatory COVID-19 patients. The phase 2/3 clinical trial linked REGN-COV2 to a 57% decline in medical visits associated with COVID-19 in the 29 days after treatment. read more By Ben Adams Sanofi is teaming up with Merck while AstraZeneca taps Arcus as the future of cancer work is very much made together. read more By Amirah Al Idrus Vedere Bio didn’t stand a chance. The Atlas Venture gene therapy startup was working under the radar on its vision loss candidates and contemplating another venture round when it got an offer from Novartis it couldn’t refuse: $150 million up front, plus $130 million more if it hit certain goals. read more By Amirah Al Idrus Just five months after coming out of stealth, Q32 Bio is back for round two. The autoimmune player raised $60 million from the likes of OrbiMed, Atlas Venture and Abingworth to push its lead antibody through the clinic and bolster its pipeline and the technology behind it. read more By Amy Sokolow Drug companies often face steep challenges when entering new markets for the first time, and certain markets struggle to access much-needed drugs in a timely fashion. That’s where LianBio comes in. read more By Ben Adams Syneos Health is buying out midsized, late-stage focused contract research organization Synteract to help bolster its research services footprint. read more By Conor Hale Shortly after announcing plans to transform itself into a digital, “cloud-first” drugmaker, Takeda has extended its agreements with Seqster—a company whose founder describes it as the Mint.com of patient healthcare data. read more Resources Sponsored By: Paysign In this case study on the Alec Smith Insulin Affordability Act, you will learn not just about the law but about the portal platform designed to change the entire process for manufacturers, pharmacists, and patients. Sponsored By: Veeva Learn how to plan immersive digital event experiences Sponsored by: Aldevron Gene and cell therapy organizations are asked to balance the need for rapid clinical progression and stringent quality expectations throughout development. 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