AstraZeneca's COVID-19 vaccine 70% effective, shares fall Merck inks $425M OncoImmune buyout to bag COVID-19 drug Amgen kicks heart failure med back to Cytokinetics after 'GALACTIC' flop ATAI snags $125M to bankroll mental health pipeline Belgium biotech argenx nabs Bayer speedy review voucher for a cool $98M Catamaran Bio sets sail with $42M to create off-the-shelf CAR-NK treatments Black Diamond's EFGR-targeted glioblastoma drug candidate slows tumor growth in mice Schrödinger's in-house pipeline helps fetch $2.7B molecule discovery deal with BMS Regeneron, following in Lilly's footsteps, wins FDA emergency nod for COVID-19 antibody cocktail Featured Story | By Nick Paul Taylor AstraZeneca’s COVID-19 vaccine has achieved 70% efficacy in a late-phase analysis. The 70% figure is an average that masks variation in the performance of two dosing regimens, one of which was found to be 90% effective. read more |
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Top Stories By Nick Paul Taylor Merck has struck a deal to buy OncoImmune for its COVID-19 treatment CD24Fc. The $425 million cash acquisition will give Merck control of a fusion protein linked to improvements in clinical status in a phase 3 trial of severe and critical COVID-19 patients. read more By Amirah Al Idrus After more than a decade working on heart failure programs with Cytokinetics, Amgen is handing two programs back to its partner. The move comes after their more advanced program beat placebo in a phase 3 study at warding off hospitalizations and other interventions in patients with a type of chronic heart failure—but did not help them live longer. read more By Amirah Al Idrus ATAI Life Sciences is topping off a busy year with a $125 million financing, which will support the preclinical and clinical development for its mental health pipeline, including programs in opioid use disorder and depression. The series C round follows a $43 million round in March 2019. read more By Ben Adams Big Pharma friend argenx has snapped up an FDA priority review voucher from Bayer for $98 million. read more By Amirah Al Idrus Cell therapies have seen success in some blood cancers, but the same can’t be said for solid tumors. Several biotechs have sprung up to close that gap in different ways, but Catamaran Bio thinks single “linchpin” approaches won’t be enough. Instead, it’s taking a multipronged approach shepherded by a team of cell therapy and biopharma veterans. read more By Arlene Weintraub Black Diamond Therapeutics is targeting glioblastoma with its drug BDTX-1535, which is designed to cross the blood-brain barrier and inhibit several allosteric EGFR mutations. In mice, the drug inhibited tumor growth without affecting non-mutated forms of EGFR. read more By Conor Hale Like AstraZeneca, Bayer and Sanofi before it, Bristol Myers Squibb has now tapped molecule modeler Schrödinger for a drug discovery collaboration spanning multiple disease areas. read more By Angus Liu Regeneron's COVID-19 antibody cocktail, one of the drugs President Donald Trump took after being infected with the virus, has been cleared for emergency use by the FDA in an authorization that's almost identical to that of Eli Lilly's. Despite looming rollout of vaccines, one analyst sees the therapy as a steady $1 billion-plus asset. read more Resources Sponsored By: Oracle Health Sciences New research indicates an accelerated adoption of decentralized clinical trials due to COVID-19. Sponsored By: Veeva New industry-wide research reveals that the quality and breadth of HCP data is imperative as commercial teams adjust to remote engagement and execute a tailored approach. 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