Protara jumps, Cyclacel slumps after updates

Today’s Big News

Dec 6, 2024

Chasing Merck, BioNTech and DualityBio post first clinical data on ADC


AstraZeneca, Daiichi share data behind Dato-DXd do-over amid 2nd bid for lung cancer approval


What can we learn from 2024’s biotech IPOs?


Protara shares spike after cell therapy shows high response rate, no severe side effects in bladder cancer trial


Cash-strapped Cyclacel cuts costs as it searches for financial lifeline


Chutes & Ladders—Stanford economist is Trump's NIH pick

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Chasing Merck, BioNTech and DualityBio post first clinical data on ADC

Duality Biologics has shared the first data from a phase 1/2a antibody-drug conjugate trial, giving an early look at how the BioNTech-partnered asset is shaping up against rival molecules in development at companies including Merck & Co.
 

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AstraZeneca, Daiichi share data behind Dato-DXd do-over amid 2nd bid for lung cancer approval

AstraZeneca and Daiichi Sankyo have shared the data they believe can secure approval for datopotamab deruxtecan at the second attempt. The partners showed off subgroup overall survival data that exceeded the result seen in the broader population, providing evidence to support the pivot.

What can we learn from 2024’s biotech IPOs?

This week on "The Top Line," we explore the biotech IPO market rebound and ask: Is the momentum here to stay?

Protara shares spike after cell therapy shows high response rate, no severe side effects in bladder cancer trial

At six months, Protara Therapeutics’ investigational cell therapy elicited a complete response rate of 72% among 18 patients with bladder cancer, data that sent the biotech’s shares surging.

Cash-strapped Cyclacel cuts costs as it searches for financial lifeline

Cyclacel Pharmaceuticals will begin to slash its operating costs as the cancer-focused biotech explores "strategic alternatives on an expedited basis."

Chutes & Ladders—Stanford economist is Trump's NIH pick

President-elect Donald Trump has chosen Stanford University’s Jay Bhattacharya, M.D., Ph.D., to serve as the director of the National Institutes of Health. Bhattacharya is a physician, professor and economic researcher known for co-authoring a controversial open letter in October 2020 that called for an end to pandemic lockdowns.

PreciseDx's digital pathology AI on par with genomic testing in predicting breast cancer recurrence risks: study

Working with the real-world cancer data company COTA Healthcare, the former Fierce 15 winner put up its PreciseBreast test against Exact Sciences’ Oncotype DX.

On an investment spree, Lilly will spend $3B to expand newly acquired injectables plant in Wisconsin

Eli Lilly said it will spend $3 billion to transform a newly acquired, 84,000-square-foot plant in Kenosha, Wisconsin, into a massive complex that will produce injectables, including the company’s top-selling diabetes and obesity drugs Mounjaro and Zepbound.

Primary care market will see major shifts by 2030 as payers, nontraditional providers gain ground

Nontraditional providers will account for about one-third of the primary care market in 2030, according to Bain & Company. Payer-owned primary care, population-focused models and advanced primary care providers are all poised for growth.

Fierce Pharma Asia—Sanofi's $1B manufacturing base; GSK's ADC deal, Shingrix recalibration in China

Sanofi unveiled a plan to build a $1 billion manufacturing site in Beijing while completing construction at a plant in Singapore. GSK inked an antibody-drug conjugate deal with DualityBio and, through a revised agreement with Zhifei, dialed down its expectations for Shingrix in China for the next few years. And more.
 
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What can we learn from 2024’s biotech IPOs?

This week on "The Top Line," we explore the biotech IPO market rebound and ask: Is the momentum here to stay?
 

Resources

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Building a “Best Practice” R&D Organization in Biopharma

We interviewed 14 R&D biopharma leaders on the critical success factors for building a Best Practice R&D organization. This report shares what we learned.
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Single Cell RNA Profiling FFPE Tissue

Explore the robust cross-platform agreement between scRNA-seq and bulk RNA-seq, ensuring consistent and reproducible data on immune cell presence.
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Straight to Market in an Autoinjector

The use of prefilled syringes to administer biotherapeutics is beginning to gain traction because they offer a range of stability, efficacy, and patient safety benefits. Download this white paper to learn how Lonza has developed a novel workflow to ensure confidence regarding functionality in PFS and autoinjectors.
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Planning for success in cell-based manufacturing

Learn how to evaluate quality documentation to help you select the right raw materials at early decision points for your cell-based manufacturing processes.
 

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On Helix

Date: ‌4 ‌July ‌2024 ‌- ‌Location: ‌Babraham ‌Research ‌Campus, ‌Cambridge ‌UK

 

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