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December 10, 2018

Today's Rundown

Featured Story

Axovant dumps nelotanserin in retreat from small molecule R&D

Axovant has halted development of nelotanserin after it missed the primary endpoint in a phase 2 trial in patients with Lewy body dementia. The lackluster data persuaded Axovant to drop the drug and complete its pivot from small molecules to gene therapies.

Top Stories

MacroGenics halts trials of cancer drug after FDA partial hold

Potential liver-related side effects have led to the FDA placing a partial clinical hold on a MacroGenics-developed bispecific antibody for cancer.

Gritstone ramps up bispecifics with new antibody therapeutics chief

Gritstone Oncology has appointed Jonah Rainey, Ph.D., to head up its bispecific antibody program as it moves into lead optimization.

Novo taps e-therapeutics for diabetes target discovery drive

Novo Nordisk has enlisted e-therapeutics to support target discovery efforts at its recently opened research center in Oxford, U.K. The collaboration will see e-therapeutics apply its platform for finding synergistic target combinations to a “specific area” of Type 2 diabetes.

Junshi Biosciences aims for $414M Hong Kong IPO: Reuters

China’s Junshi Biosciences may follow in compatriot Innovent Biologics’ footsteps as it tees up to raise $414 million in its Hong Kong IPO, Reuters reported. It’s the latest company looking to list on the Hong Kong Stock Exchange after it relaxed its rules for early-stage biotechs.

Gilead, looking for cancer sales, swipes Roche pharma chief Daniel O'Day for CEO post

With Gilead Sciences' CEO on the way out and hepatitis C revenues tumbling, the company needs a leader who can pump up in oncology. And hoping to find just that, it has poached a top executive from the biggest cancer drug maker in the world.

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[Whitepaper] In-House Versus Outsource: A Decision-Making Guide

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[Report] Clinical Operations Report: Learn the Top Industrywide Priorities

Industry Research: Read the 2018 Unified Clinical Operations Report to find out how pharmas and CROs are evolving clinical trial processes.

[Webinar] QSP Approaches to Determine Best in Class Properties for Targeted Anabolic Growth Factor to Arthritic Joints

This on-demand webinar introduces a quantitative systems pharmacology (QSP) model of targeted anabolic growth factors for intra-articular injection for the treatment of diseased joints.

[Research Report] Challenges And Opportunities In Clinical Data Management

New research reveals more than 50% of clinical data management professionals surveyed, are not confident in the quality and completeness of their clinical trial data.

[Whitepaper] Migraine Treatment and Calcitonin Gene-Related Peptide Inhibitors: Real-World EHR Case Study

New Case Study – Leveraging Real-World Evidence From EHR to Assess Migraine Management

[Whitepaper] The Future of Cell & Gene Therapy

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[Whitepaper] Why Life Sciences Companies Leverage Managed Regulated Infrastructures

Outer Edge Technology specializes in designing and managing regulated cloud-based infrastructures for the Life Sciences Industry – typically leveraging the AWS and Microsoft Azure platforms.

[eBook] 2018 Weekly Compendium

The Biopharma industry is moving at lightning speed and it can be a challenge to keep pace. Here at Biotech Primer we spend hours each week researching, writing, and editing original content for the Biotech Primer WEEKLY with one goal in mind: to help everyone better understand the latest science and technology driving today’s healthcare industry.

Events