Ikena merges with Inmagene after tough year

Editor's Note: This is the last issue of Fierce Biotech in 2024. Starting tomorrow, the Fierce team will be taking a break for the holidays. Fierce Biotech will be back in your inbox on Jan. 2, but be sure to visit the website for the latest news until then. We hope you have a great holiday season and a happy New Year.

Today’s Big News

Dec 23, 2024

Fierce Biotech's top 10 editor's picks for 2024 


Editor's Corner: Fierce Biotech's 10 most-read stories of 2024


Ikena, after tough year of layoffs, merges with Inmagene to focus on phase 2 dermatitis prospect


Rapt re-rolls after flameout, paying $35M for challenger to Novartis, Roche drug


Sanofi pays SK bioscience €50M as children's pneumococcal vaccine enters phase 3


Phase 2 data will drive biopharma VC investments next year: PitchBook


Applied Therapeutics CEO steps down in wake of FDA rejection, warning letter and investor lawsuit


Galectin's MASH treatment reduces varices but fails to hit statistical significance in phase 3 trial

The Top Line Podcast: Don’t miss out on the newest episode. Listen now.

 

Featured

Fierce Biotech's top 10 editor's picks for 2024

From the conference circuit to the Nasdaq trading floor, we run down some of the highlights from Fierce Biotech's coverage this year.
 

Top Stories

Editor's Corner: Fierce Biotech's 10 most-read stories of 2024

For the end of this year, Fierce Biotech is taking the opportunity to reflect on trends emerging from 2024’s reporting. And readers have made it easy for us—it’s clear what kind of story drew the most interest.

Ikena, after tough year of layoffs, merges with Inmagene to focus on phase 2 dermatitis prospect

After a year that saw Ikena Oncology trim back its workforce and pipeline, the oncology biotech thinks it’s found a sustainable path forward via a merger into privately owned immunology company Inmagene Biopharmaceuticals.

Rapt re-rolls after flameout, paying $35M for challenger to Novartis, Roche drug

Rapt Therapeutics has charted a new course following the implosion of its lead program, agreeing to pay $35 million for a long-acting challenger to Novartis and Roche’s Xolair.

Sanofi pays SK bioscience €50M as children's pneumococcal vaccine enters phase 3

Sanofi is handing SK bioscience 50 million euros ($52 million) to take their next-gen pneumococcal conjugate vaccine program into phase 3.

Phase 2 data will drive biopharma VC investments next year: PitchBook

Phase 2 trial data will continue to be the name of the game when it comes to VC investments into biopharma in 2025, according to PitchBook.

Applied Therapeutics CEO steps down in wake of FDA rejection, warning letter and investor lawsuit

A turbulent month at Applied Therapeutics is being capped off with the departure of CEO and chair Shoshana Shendelman, Ph.D., mere days after she and the company were named in a proposed class action lawsuit.

Galectin's MASH treatment reduces varices but fails to hit statistical significance in phase 3 trial

Galectin Therapeutics’ stock has halved since the company revealed its investigational drug failed to significantly reduce enlarged veins for people with liver scarring.

Clinical research company Javara lays off employees as part of restructuring

Clinical research firm Javara has laid off staff as part of a restructuring, a spokesperson confirmed to Fierce Biotech in an email.

Editor's Corner: Recapping Fierce Pharma's top stories of the year

For many readers, the topics featured in this year’s roundup of top stories won’t come as much of a surprise. Look no further than our top two stories of the year, and you’ll see that the GLP-1 craze and Big Pharma layoffs took center stage in 2024.

Congress passes spending bill with essential healthcare programs set to expire April 1

Both chambers of Congress passed legislation to fund the government on Friday night.
 
Fierce podcasts

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Integrating social-emotional learning in child education

This week on "Podnosis," we explore how teaching kids social-emotional skills early can transform their lifelong wellbeing.
 

Resources

Whitepaper

Building a “Best Practice” R&D Organization in Biopharma

We interviewed 14 R&D biopharma leaders on the critical success factors for building a Best Practice R&D organization. This report shares what we learned.
 

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