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MAY
22
THIS WEEK
  NEWS
  "Undruggable" Cancer Target May Have Met Its Match
  NEWS
  Microbubbles and Gene Therapy Help Heal Broken Bones
  PRODUCT ANNOUNCEMENT
  Platform Launched for Laboratories Looking to Reduce Energy Costs
  NEWS
  Cancer Drug Effective for Heart Failure Treatment, Preclinical Study Shows
  NEWS
  Researchers Develop Protocol to Analyze Many Cells at Once

Assessing Autophagy Utilizing Benchtop Flow Cytometers

MilliporeSigma

Having the ability to accurately measure autophagosome activity via LC3 translocation, as well as perform deep-dive analysis of small molecule activity by deriving dose response curves, can greatly enhance studies of cancer, neurodegeneration, and other diseases affected by autophagy. This application note describes several new optimized assay kits specifically designed for autophagy evaluation by flow cytometry.

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FEATURED STORY

Beyond Just Promise, CRISPR is Delivering in the Lab Today

Featured Story

Researchers are starting to harness the potential of this much-hyped gene editing technique - with coming applications in medicine, biology and agriculture.


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Sample Preparation for the Detection of Synthetic Analogues of Insulin in Human Serum

Genevac LTD

Due to an increase in the abuse of synthetic insulins, doping laboratories require faster and more consistent testing options. The methodology to detect and confirm the presence of peptide hormones by mass spectrometry is preferred to the current use of immunoassays or other immuno-reactive techniques. This white paper explores and compares the different available methods, revealing the fastest and most accurate options for synthetic insulin detection.


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NEWS

"Undruggable" Cancer Target May Have Met Its Match

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South Korean scientists recently published data showing that novel, cell-penetrating antibodies targeting the RAS gene family, produce anti-tumor activity in mice.


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NEWS

Microbubbles and Gene Therapy Help Heal Broken Bones

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Researchers from Cedars Sinai Medical Center have developed a new technique that, if successful in humans, could replace traditional bone grafts for mending nonhealing limb fractures. The new method, which combines, microbubbles, ultrasound, and gene and stem cell therapies, effectively healed severely broken bones in a study in pigs.


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Facilitating Discrimination Between Induction of DNA Damage, Oxidative Stress and Protein Misfolding Using a Novel Multicell GFP Reporter Assay

MilliporeSigma

Utilizing benchtop flow cytometry, new novel multicell GFP reporter assay was developed to help facilitate discrimination between induction of DNA damage, oxidative stress and protein misfolding.


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FOCUS ON:

Platform Launched for Laboratories Looking to Reduce Energy Costs

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Aircuity, creator of measurably better environments, announced the launch of its 2.0 platform. Aircuity 2.0 is ideal for research laboratory facilities looking to significantly reduce energy costs, monitor space conditions and occupant behavior, and achieve quantifiable savings that can be reinvested in research.


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NEWS

Cancer Drug Effective for Heart Failure Treatment, Preclinical Study Shows

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Researchers from the Gladstone Institutes have discovered newly-developed cancer drugs may also provide a treatment option for heart failure patients.


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Limitations and Requirements for Measuring Metabolic Rates: A Mini Review

Sable Systems International

Metabolic measurement of humans and animal models is an important aspect of biomedicine. However, the limitations of current methods in metabolic measurement are not widely understood. This mini-review explains the methodological trade-offs involved in metabolic measurement with flow-through respirometry and specifically addresses limitations regarding temporal resolution and accuracy of metabolic measurement systems with practical solutions.


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NEWS

Hallucinogen May be Potential Fast-acting Treatment for OCD

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The first time psychiatrist Carolyn Rodriguez gave an infusion of ketamine to a patient with obsessive-compulsive disorder, she was nervous. After all, while ketamine is approved by the FDA as an anesthetic, it is also an illicit party drug known as "Special K." But the results simply astonished her


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NEWS

Researchers Develop Protocol to Analyze Many Cells at Once

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Researchers have developed a new way to analyze hundreds of thousands of cells at once, which could lead to faster and more accurate diagnoses of illnesses, including tuberculosis and cancers.


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NEWS

Chronic Pain Amplifies the Brain's Reaction to New Injuries

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Chronic pain in any one body part may distort the intensity with which a key brain region perceives pain everywhere else.


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NEWS

Scientists Enlist Engineered Protein to Battle MERS Virus

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A custom-engineered protein destroyed the deadly virus in the lab and could become a sweeping anti-viral in medicine and farming.


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Bioscience Technology
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