| Dear Voornaam
Have you heard of FAIRification, or the process of making data FAIR?
In our latest Research with Integrity column, Andrew Porter (Research Integrity and Training Adviser at the Cancer Research UK Manchester Institute) and Kate Kamieniecka (Lead Data Steward Trainer, ELIXIR-UK Fellowship) get into how and why to make your data Findable, Accessible, Interoperable, and Reusable (FAIR).
Most cancer researchers are now data scientists in a way undreamt of 40 years ago. This combined with the tight demands placed on researchers time means that the FAIR principles are too often not prioritised.
Find out why you should apply FAIR data principles for research in our latest blog. |
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Funding & Research Opportunities |
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| | | Applications accepted all-year round |
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| | | Applications accepted all-year round |
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IAN WALKER REFLECTS ON HEALTH AND CANCER INEQUALITIES With more than 30,000 extra cases of cancer in the UK each year attributed to socio-economic variation, there is clearly much work to do in this area.
Writing in Cancer News, Ian Walker, our Executive Director of Policy, Information and Communications, talks about the work hes leading to influence government, make our About Cancer pages more accessible to different communities and spread best practice to healthcare organisations and professionals. |
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TOPOGRAPHY OF MUTATIONAL SIGNATURES IN HUMAN CANCER Burak Otlu, Ludmil B. Alexandrov and colleagues have published results showing that mutations imprinted by mutational signatures are affected by topographical genomic features.
The new study in Cell Reports describes how they integrated mutations from 5,120 whole-genome-sequenced tumours from 40 cancer types with 516 topographical features.
They evaluated the effect of nucleosome occupancy, histone modifications, CTCF binding, replication timing, transcription/replication strand asymmetries, genic versus intergenic regions and strand-coordinated mutagenesis on the cancer-specific accumulation of mutations from mutagenic processes.
The findings from the Cancer Grand Challenges Mutographs team have been added to the COSMIC signatures database, providing a comprehensive online resource for exploring the interactions between mutational signatures and topographical features within and across cancer types. |
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 FIRST PATIENT DOSED WITH SOSEI HEPTARES NOVEL CANCER IMMUNOTHERAPY DRUG The first patient has been dosed in the Phase 1/2a trial carried out by our Centre for Drug Development to investigate HTL0039732s effect on patient survival. The drug selectively blocks the EP4 prostaglandin receptor associated with tumour cell growth and immune evasion.
The drug is a potential candidate for patients with a range of cancers including colorectal, gastroesophageal, head and neck and prostate cancer. If successful, it will bring effective treatment closer to these underserved patient populations. |
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|  PRESENT YOUR WORK AT OUR CHILDRENS
AND YOUNG PEOPLES CONFERENCE Are you an early-career researcher working in children's and young people's cancer? Submit an abstract before 6 September to be selected for a lightning talk at our upcoming children's and young people's cancer research conference.
You'll have the chance to speak alongside Pam Kearns (University of Birmingham), Sam Behjati (Wellcome Sanger Institute), Katrin Ottersbach (University of Edinburgh) and Steve Clifford (Newcastle University) and get invaluable feedback and recognition on your project. |
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MEET OUR LATEST GRANT AWARDEES A big round of applause to the newest grant awardees selected by our Research Careers Committee in the May funding round:
Amaya Viros was granted an Advanced Clinical Science Fellowship, and Andrew Blackford received a Senior Cancer Research Fellowship. Mirjana Efremova was selected for a Career Establishment Award, while Sarah Aitken was awarded a Clinician Scientist Award.
Khaylen Mistry, Riccardo Masina, Daniele Scotto and Georgios Solomou received Pre-doctoral Research Bursaries, while Thomas Hubbard, Akshay Patel and Robert Morgan were awarded Postdoctoral Research Bursaries. |
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 REGISTRATION OPEN FOR CAMBRIDGE LUNG CANCER SYMPOSIUM The wait is over! If you work in the field of lung cancer, register now for the Cambridge Lung Cancer Symposium on 3 November 2023 at the Cancer Research UK Cambridge Institute.
You will be joining national and international lung cancer leaders and researchers working in discovery, clinical and translational aspects to share progress and foster new collaborations.
The symposium is organised by the Thoracic Cancer Programme at our Cancer Research UK Cambridge Centre. |
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|  NURTURE YOUR ENTREPRENEURIAL TALENT WITH THE LEAN LAUNCH PROGRAMME The Cancer Research Horizons Lean Launch Programme is a 10-week online market discovery programme that will provide funding and support with a wide network of entrepreneurs, investors and funders.
Want to know more? Make sure to come to the information session at 12PM on 17 August to find out more about how the Lean Launch Programme can help you explore your oncology-related innovation. |
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ABOUT TO PUBLISH YOUR RESEARCH? DONT FORGET TO KEEP US IN THE LOOP Are you preparing a Cancer Research UK-funded research paper for publication? If so, wed love to hear about it.
You can let us know about pending publications via our manuscript notification form. All information will be treated confidentially and will not be used without consulting you first.
Knowing in advance about upcoming publications helps us plan our communications and allow us to better talk to our supporters about the work that their donations help fund. |
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| | | London, UK & Online 26 September 2023 |
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| | | Online 4:00 PM 27 September 2023 |
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| | | Paris, France 04 October 2023 |
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| | | London, UK 10 October 2023 |
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| | | Liverpool, UK 18 October 2023 |
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| | | Manchester, UK 03 November 2023 |
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| | | London, UK 14 November 2023 |
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| | | London, UK 21 November 2023 |
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| | | Manchester, UK 27 February 2024 |
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