Cancer Research ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏
| | A recent perspectives article in Cell by Charles Swanton, Karen Vousden, Doug Hanahan and others, explores how technological advances are providing new insights into the complexities of cancer. The review emerged from discussions at our 4th annual symposium in memory of Chris Marshall which brought together leading experts to examine the interplay between tumour micro and macroenvironments from all angles. The paper explores the genetic mutations which drive tumour promotion and progression, chronic inflammation and how this could affect mutated cells and the role of lifestyle factors and circadian rhythms amongst many other themes. |
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Funding & Research Opportunities |
| Get in touch with our office for confidential advice on eligibility, remit and funding options prior to applying. |
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| | | | | | | Applications accepted all year round |
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| | | | Applications accepted all year round |
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| | | | Applications accepted all year round |
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Call for in vitro researchers to participate in user testing new reporting standards |
| The NC3Rs is testing new reporting standards to improve the reliability and reproducibility of in vitro studies and is offering expert feedback on manuscripts in progress. If you use in vitro models in your research, find out more about the Reporting In Vitro Experiments Responsibly (RIVER) recommendations user testing study from the NC3Rs. Get in touch by 30 April to take part in the current round of user testing. Participants in the current round will need to send their draft manuscript by 17 May. |
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| | The agenda for our postdocs event in Manchester on 7 June is taking shape. Chiat Cheong, a former postdoctoral researcher turned researcher career development consultant, will lead an interactive careers session. This session will guide you to develop the tools and framework to take your next step into a fulfilling career. Chiat will also chair a lightning talk session on inspirational career journeys from people who started as cancer research postdocs and moved into related sectors, all still contributing towards improving cancer outcomes. Stay tuned to hear who will be joining us for that session. | |
| | | | In a recent Cell Genomics paper, an international team headed up by David Woodcock, at the University of Oxford, and David Wedge from the Cancer Research UK Manchester Centre propose an “evotype” model for prostate cancer evolution. Using several methods to classify the tumour data sets, they’ve identified two distinct types of prostate cancer emerging from different evolutionary pathways. The study findings present significant implications for our understanding of prostate cancer that could allow tumours to be classified based on how the cancer evolves rather than solely on individual gene mutations or expression patterns. The concepts are relevant to numerous tumours, so could offer insights into risk stratification and disease behaviour across various types of cancer. | |
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What's new at this year's Brain Tumour Conference? |
| The final conference programme includes keynotes from Arnold Kriegstein (University of California, San Francisco) and Karen Vousden (The Francis Crick Institute), patient-led talks and sessions with world-leading scientists addressing some of the hottest topics in the field. Hear from Bissan Al-Lazikani (MD Anderson Cancer Center), Simona Parrinello (University College London), Sriram Venneti (University of Michigan) and Juanita Lopez (The Royal Marsden/The Institute of Cancer Research) showcasing their expertise on artificial intelligence, model organisms and clinical trials. |
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