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| | | Elucidating PROTAC MoA with live cell kinetic monitoring of ternary complex formation and target protein ubiquitination |
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| PROteolysis TArgeting Chimeras (PROTACs) are small molecules that selectively induce protein degradation and are seen as promising therapeutics.
In this application note, NanoBRET™ is used to measure targeted protein degradation in live cells upon PROTAC treatment.
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