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| | Date issued: 22 April 2024 This ebulletin contains details of an upcoming training event focussing on the toxicological endocrine disruption (ED) assessments of pesticides and biocides under the Plant Protection Products (PPP) and Biocidal Products (BP) regimes in Great Britain and Northern Ireland. For more information visit ourChemicals Regulation Division (CRD) training and eventswebpage. |
| 17 and 18 July 2024 This event will focus on the toxicological ED assessment of pesticide and biocide active substances and biocide products and will present the current evaluation approach used by HSE. The training will be delivered by HSE regulatory specialists and will include sessions on the guidance currently available. The focus will be on helping attendees understand how to improve the quality of their applications by demonstrating how these dossiers are assessed by HSE as the regulator responsible for approvals and authorisations under the BP and PPP regimes. Who should attend? Those who already carry out toxicological endocrine disruptor assessments of pesticide and biocide substances and biocide products or have an interest in the evaluation approach used by HSE. Topics covered: ED criteria for pesticide and biocide active substances and associated European Chemicals Agency/European Food Safety Authority guidance
Overview of toxicology ED assessment scheme for biocide/pesticide active substances General approach and information sources for adversity and activity Specificity of adverse effects Organisation for Economic Co-operation and Development Conceptual Framework for testing and assessment of EDs
Templates, spreadsheets, and assessment guiding principles
Assessment of T (thyroid) modality, including data gaps, MoA (mode of action) analysis and DNT (developmental neurotoxicity) considerations
Case studies to illustrate T modality assessment with potential different outcomes
Assessment of EAS (estrogen-androgen-steroidogenesis) modalities, including deficient datasets, data gaps and MoA analysis
Case studies to illustrate EAS modalities assessment with potential different outcomes
Endocrine disruption assessment of co-formulants in biocidal products Registration: Find out more and register for this fee paid training event The closing date for registration is 9 July 2024. |
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Health and Safety Executive - 5N1 Redgrave Court, Merton Road, Bootle, Merseyside L20 7HS
