#skinlongevity
"The cosmetics industry is shifting towards a more holistic view of aging, focusing on skin longevity. Moving away from anti-aging narratives, the emphasis is now on preventive solutions to support long-term skin health by addressing aging at its root causes, especially cellular senescence.
This biological process, where cells cease to divide due to stress or damage, can contribute to aging by altering tissue structure. Senescent cells release the SMS (Secretome Messenger of Senescence), which can induce senescence in nearby cells, promoting contagious aging.
Key triggers include DNA damage, oxidative stress or nuclear dysfunctions like lamin A deficiencies, a protein vital for cell function.
Different ways can be considered to cope with senescence, by targeting the triggers or the outcomes. “Juvenessence”, an Alaria esculenta extract, reduces Progerin, a degraded form of Lamin A, while “Aspar’age” helps regulate the effects of contagious aging. This active ingredient, thanks to mycosporine like amino acids, is able to protect young fibroblasts from senescence by lowering IL-6 secretion and reducing β-galactosidase activity, effectively mitigating the senescence of nearby young cells."
