By using rod-shaped nanoparticles, in combination with inhibitors to other uptake pathways, researchers achieved targeting cancer cells over healthy cells. The possible benefits from this novel technique are twofold: Restricting healthy cells from taking anticancer drugs to help reduce the side effects of drugs for patients; and helping overcome chemoresistance (the uptake of the chemo drug into healthy cells in the tumor setting is one of the main causes of chemoresistance).