November 2022 Clinical Digest

Overall, there is not enough scientific evidence to show that any dietary supplement can help manage or prevent type 2 diabetes. Some dietary supplements may provide some benefit for some conditions associated withtype 2 diabetes. It is important to note, however, that there are multiple case reports linking dietary supplement use to kidney disease, which is of particular concern because diabetes is the leading cause of chronic kidney disease and kidney failure in the United States. Supplement use should be monitored closely in patients who have or are at risk for kidney disease.

Both learning and verbal instructions influence expectations and peoples perception of pain, but responses differ in different regions of the brain, according to a new study by researchers from the National Institutes of Health, published ineLife.The findings of this study, which was conducted by the intramural research programs of the National Center for Complementary and Integrative Health and the National Institute of Mental Health, may help researchers develop better treatments for pain.

Contrary to the findings of a study published 2 years ago, the ion channel Piezo1 does not react to microbial single-stranded RNA (ssRNA) in the gut, according to a new study by investigators from the National Center for Complementary and Integrative Health (NCCIH) and The Scripps Research Institute. The new study, which was funded by the Helping to End Addiction Long-termInitiative, or NIH HEAL Initiative, was published in the journaleLife.