Assessing the benefits and risks of vaccinations in young people Since the rollout of the COVID-19 vaccination campaign, it has been vital to monitor the impact of vaccinations on mortality. As with any vaccine, this includes assessing the protection the vaccine offers against infection and severe outcomes, but also measuring the potential side effects and adverse events. The balance of risk and benefit becomes particularly important in groups where the likelihood of severe outcomes from COVID-19 is lower, as in younger people. Here, Charlotte Bermingham discusses new ONS analysis on vaccine safety in the context of young people.â¯Â | 