Well, well, well. It's the final Wednesday before the 2022 NFL season. John Breech can't contain his excitement for Joe Burrow's return to the field this coming weekend, so he's excused himself from work. But you've got me, Cody Benjamin, to deliver all the latest from around a busy NFL.

This is the Pick Six Newsletter. Now let's get to it. (And please, do yourself a favor and make sure you're signed up to receive this newsletter every day! You don't want to miss our daily offerings of everything you need to know around the NFL.)

We've got Week 1 picks, QB power rankings, major Jets news, and much more:

The "Pick Six NFL Podcast" crew did a final preseason mailbag on Tuesday in anticipation of the new season. On Wednesday, the guys are set to reunite for a look ahead to potential 2022 awards winners, forecasting candidates for MVP, Comeback Player of the Year and other notable accolades. Can Josh Allen get his first NFL MVP? Or is a previous winner, like Patrick Mahomes or Aaron Rodgers, more poised to take home the top honor this time around? You're not gonna wanna miss the debate.

Catch the full episode (and subscribe for all kinds of daily NFL talk) right here.

Major news on the Big Apple injury front, with Jets coach Robert Saleh announcing Wednesday that second-year starter Zach Wilson won't likely be available until at least Week 4 as he recovers from knee surgery. Wilson suffered a torn meniscus during the team's preseason opener, and now he's expected to have to wait until October to kick off his 2022 season. In the meantime, 37-year-old backup Joe Flacco will take over under center, starting with a Week 1 showdown with his old team, the Ravens.

Pete Prisco's weekly predictions are back, and he's feeling good heading into the year. Here's a sneak peek at his Week 1 picks:

• Bills 30, Rams 24: Buffalo will be explosive on offense all year and it starts here. But the biggest difference is they have Von Miller and the Rams don't. That will mean sack-fumble-game-over late for the Bills to win it.
• Panthers 23, Browns 17:  Mayfield has a lot of skill talent around him and the Panthers' young defense will be improved. Carolina wins it as Mayfield beats his old team.
• Cowboys 20, Buccaneers 17: These two both come into the game with concerns on their offensive lines. That's a problem for Tom Brady, who doesn't move that well. Dak Prescott  will be able to handle himself by moving around and creating problems outside the pocket. The Cowboys will win a tough, defensive game to get off to a 1-0 start.
  

Lamar Jackson and the Ravens respect each other, and they're focused on winning together in 2022. Just don't count on them striking a long-term deal anytime soon, according to CBS Sports NFL Insider Jonathan Jones:

Though neither side is detailing snags in contract negotiations, the prevailing thought is that guaranteed money is among the central issues here. ... One source familiar with the negotiations told me it seems as though Jackson's feelings are "if it happens, great." Jackson is comfortable playing the fifth-year option of $23 million should a deal not get done in the coming days. "He's confident," another source said. "He knows he's going to produce. Where's the urgency if you know you're gonna produce?"

Every week during the season, we rank all 32 starting quarterbacks from first to worst, based on which signal-caller we'd most prefer both now and for the remainder of the year. Here's a look at our first top 10 of the 2022 season:

1. Patrick Mahomes (Chiefs)
2. Tom Brady (Buccaneers)
3. Aaron Rodgers (Packers)
4. Josh Allen (Bills)
5. Justin Herbert (Chargers)
6. Joe Burrow (Bengals)
7. Russell Wilson (Broncos)
8. Lamar Jackson (Ravens)
9. Matthew Stafford (Rams)
10. Dak Prescott (Cowboys)

Hungry for more headlines? We've got you covered:

• Five bold predictions for 2022: Tyler Sullivan foresees a monster year for Russell Wilson
• Teams that could shock fans this season: Jordan Dajani has the Saints among his sleepers
• Top 10 breakout candidates: Chris Trapasso likes him some Trey Lance in San Francisco
• Bills extend Dawson Knox: The tight end gets a lucrative four-year deal
• Odell Beckham Jr. teases his next team: And his hint has to do with Thursday night's game
• Bears eyeing new enclosed stadium: And a multi-purpose entertainment district
• Chargers' J.C. Jackson likely out for Week 1: The cornerback is still recovering from ankle surgery
• Jalen Ramsey shares his secret for success: The Rams star opens up about his spiritual foundation
• Emmanuel Sanders retires after 12 seasons: The veteran is best known for his Broncos days