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Researchers uncover the biology and treatment behind a rare autoinflammatory disease Posted: 19 Aug 2021 09:52 AM PDT The absence of a protein that activates the body's antiviral defenses can cause a rare rheumatoid-like autoinflammatory condition that is treatable with an FDA-approved class of drugs known as TNF (tumor necrosis factor) inhibitors, researchers have found. |
Study supports widespread use of better masks to curb COVID-19 indoors Posted: 19 Aug 2021 09:45 AM PDT A new study is highlighting a need for widespread use of better face masks and the importance of good ventilation to mitigate the spread of COVID-19 indoors. |
Researchers discover hidden SARS-CoV-2 'gate' that opens to allow COVID infection Posted: 19 Aug 2021 08:30 AM PDT Unprecedented visualizations of SARS-CoV-2 have allowed researchers to discover how the virus enters and infects healthy human cells. Supercomputing movies have revealed how glycans -- molecules that make up a sugary residue around the edges of the SARS-CoV-2 spike protein -- act as infection 'gates' that open to allow access to our cell's receptors. |
Antibodies block specific viruses that cause arthritis, brain infections Posted: 19 Aug 2021 08:30 AM PDT Researchers have found antibodies that protect against specific mosquito-borne viruses that cause arthritis and brain infections. The findings could lead to a universal therapy or vaccine for the viruses. |
Researchers develop steerable catheter for brain surgery Posted: 19 Aug 2021 08:30 AM PDT A team of engineers and physicians has developed a steerable catheter that will give neurosurgeons the ability to steer the device in any direction they want while navigating the brain's arteries and blood vessels. The device was inspired by nature, specifically insect legs and flagella -- tail-like structures that allow microscopic organisms such as bacteria to swim. |
Blood-pressure drugs could improve colorectal cancer survival, study suggests Posted: 19 Aug 2021 08:30 AM PDT ACE inhibitors, beta-blockers and thiazide diuretics were all associated with decreased mortality in patients with colorectal cancer. |
Posted: 19 Aug 2021 08:30 AM PDT New research suggests the feasibility of a 'dream' vaccine that not only protects against SARS-CoV-2 and its known variants of concern, but also future VOCs and other animal coronaviruses with known potential to cause severe disease in humans. |
Key mental abilities can actually improve during aging Posted: 19 Aug 2021 08:30 AM PDT It's long been believed that advancing age leads to broad declines in our mental abilities. Now new research offers surprisingly good news by countering this view. |
Teens who use cannabis frequently more likely to have premature baby Posted: 19 Aug 2021 07:27 AM PDT Teenagers who use cannabis frequently may be more likely to have children born preterm, when they become parents up to twenty years later, finds a new study. The research repeatedly assessed 665 participants in a general population cohort on their tobacco and cannabis use between ages 14 to 29 years, before pregnancy. |
Flawed quality control in the brain Posted: 19 Aug 2021 07:27 AM PDT Proteins are the 'tools' of our cells – they are essential to all vital tasks. However, they are only able to do their jobs if they fold correctly and adopt their respective, very specific 3D structure. To ensure that nothing goes wrong with the folding process, it is strictly monitored in the cell. The consequences of a flawed quality control can be seen, for example, in the deposition of misfolded proteins in neurodegenerative diseases such as Alzheimer's. Researchers have now developed a mouse line that makes the state of protein balance visible in the mammalian brain for the first time. In this way, the processes of protein quality control can now be studied in healthy and diseased neurons in more detail. |
Half of pediatric opioid prescriptions are 'high risk' Posted: 19 Aug 2021 07:27 AM PDT A new study suggests that children and young adults are frequently exposed to unsafe opioid prescriptions. |
Too much time on a computer, watching TV or other sedentary activities raises stroke risk Posted: 19 Aug 2021 05:15 AM PDT Adults younger than age 60 who spent eight or more hours a day during their free time using a computer, watching TV or reading and participated in little physical activity had an increased risk of stroke. Boosting physical activity may reduce or eliminate the increased stroke risk from prolonged sedentary time. Public health efforts to increase physical activity and reduce sedentary time in adults younger than age 60 could help to lower their long-term stroke risk. |
Experts urge caution, increased education about opioid use for people with heart disease Posted: 19 Aug 2021 05:14 AM PDT Opioid overdose is a leading cause of injury-related death for adults ages 25 to 54 in the U.S. Recent data suggest that commonly used opioids for pain management may interfere with medications used to manage and treat cardiovascular disease and stroke. |
Attractiveness pays off at work — but there’s a trick to level the playing field Posted: 18 Aug 2021 05:02 PM PDT A new study found that while a 'beauty premium' exists across professions, it's partially because attractive people develop distinct traits as a result of how the world responds to their attractiveness. They build a greater sense of power and have more opportunities to improve nonverbal communication skills throughout their lives. |
Immigrants to Canada may have lower rate of stroke than long-term residents Posted: 18 Aug 2021 05:02 PM PDT Immigrants to Canada have a 33% lower rate of stroke than long-term residents, according to a new study. |
Posted: 18 Aug 2021 05:02 PM PDT The final results of the Clinical Trial of COVID-19 Convalescent Plasma in Outpatients (C3PO) demonstrate that COVID-19 convalescent plasma did not prevent disease progression in a high-risk group of outpatients with COVID-19, when administered within the first week of their symptoms. The trial was stopped in February 2021 due to lack of efficacy based on a planned interim analysis. |
Scientists growing more complex and mature heart tissue in the lab Posted: 18 Aug 2021 12:37 PM PDT A team led by researchers has generated premature cells that support early heart development but vanish soon after birth. |
Researchers bioprint an entire active glioblastoma tumor using a 3D printer Posted: 18 Aug 2021 12:36 PM PDT The 3D print of glioblastoma -- the deadliest type of brain cancer -- is printed from human glioblastoma tissues containing all components of the malignant tumor. Researchers say the breakthrough will enable much faster prediction of best treatments for patients, accelerate the development of new drugs and discovery of new druggable targets. |
How fructose in the diet contributes to obesity Posted: 18 Aug 2021 10:52 AM PDT Eating fructose appears to alter cells in the digestive tract in a way that enables it to take in more nutrients, according to a preclinical study. These changes could help to explain the well-known link between rising fructose consumption around the world and increased rates of obesity and certain cancers. |
Heat-controllable CAR T cells destroy tumors and prevent relapse in new study Posted: 18 Aug 2021 10:05 AM PDT New research builds on a body of work exploring remotely controlled cell therapies, in which the researchers can precisely target tumors, wherever they are in the body, with a local deposition of heat. The latest study shows the system cured cancer in mice, and the team's approach not only shrunk tumors but prevented relapse -- critical for long-term survival. Further studies will delve into additional tailoring of T-cells, as well as how heat will be deposited at the tumor site. |
Pancreatic cancer trials are no more diverse now than over a decade ago Posted: 17 Aug 2021 07:27 AM PDT New study shows Black, Hispanic, Indigenous and Asian Americans remain conspicuously absent from pancreatic cancer clinical trials, which is bad for science and patients alike. |
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