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Antibody with engineered peptide targets bone metastasis Posted: 24 Jan 2022 05:42 PM PST A moderate amount of a peptide-enhanced cancer drug goes a long way in treating breast cancers that metastasize to the bone. |
Why the Omicron variant causes less severe disease Posted: 24 Jan 2022 05:37 PM PST A new study shows that the SARS-CoV-2 Omicron variant is less effective than Delta at blocking a cellular defense mechanism against viruses, the so-called 'interferon response'. Moreover, cell culture findings indicate that eight important COVID-19 drugs and drug candidates remain effective against Omicron. |
Blood proteins could be the key to a long and healthy life, study finds Posted: 24 Jan 2022 05:37 PM PST Two blood proteins have been shown by scientists to influence how long and healthy a life we live, research suggests. |
Redefining alcohol use disorder Posted: 24 Jan 2022 04:49 PM PST Researchers have developed a new framework that they believe will help identify people previously overlooked for alcohol use disorder (AUD). This framework focuses on 13 risk factors, such as impulsive behavior, reward sensitivity, and punishment sensitivity, that could lead to someone developing an AUD. |
A soft, stretchable thermometer Posted: 24 Jan 2022 04:49 PM PST The next generation of soft robotics, smart clothing and biocompatible medical devices are going to need integrated soft sensors that can stretch and twist with the device or wearer. The challenge: most of the components used in traditional sensing are rigid. Now, researchers have developed a soft, self-powered thermometer that can be integrated into stretchable electronics and soft robots. |
Fast, cheap test can detect COVID-19 virus’ genome without need for PCR Posted: 24 Jan 2022 04:49 PM PST Researchers have developed a new test for COVID-19 that combines the speed of over-the-counter antigen tests with the accuracy of PCR tests that are processed in medical labs and hospitals. |
Access to vital health services fell during COVID, particularly for poorer Americans Posted: 24 Jan 2022 04:49 PM PST Some of the most socioeconomically disadvantaged patients -- those with Medicaid or Medicare-Medicaid dual eligibility insurance -- were far less likely than those with other insurance plans to return to using outpatient services at rates approaching normal, pre-pandemic levels. |
Gender disparities may be widening for physicians due to COVID-19 Posted: 24 Jan 2022 04:49 PM PST Analysis of top-ranked primary care journal before and during pandemic found pandemic disproportionately affected women. Publications are 'hallmarks of tenure decisions' and boost promotions and raises. Burnout, childcare and eldercare responsibilities may be impacting publication rates. |
Current vaccines teach T cells to fight Omicron Posted: 24 Jan 2022 12:11 PM PST Scientists have found that four COVID-19 vaccines prompt the body to make effective, long-lasting T cells against SARS-CoV-2. These T cells can recognize SARS-CoV-2 Variants of Concern, including Delta and Omicron. |
Heat dome and other climate events have growing impact on mental health Posted: 24 Jan 2022 12:10 PM PST Last summer's Western North American heat dome caused more than record-breaking temperature increases--rising anxiety about climate change is reported in a new study on the weather event's impact on our mental health. |
Researchers provide insight into how the brain multitasks while walking Posted: 24 Jan 2022 12:10 PM PST New research turns the old idiom about not being able to walk and chew gum on its head. Scientists have shown that the healthy brain is able to multitask while walking without sacrificing how either activity is accomplished. |
Artificial intelligence identifies individuals at risk for heart disease complications Posted: 24 Jan 2022 08:50 AM PST For the first time, University of Utah Health scientists have shown that artificial intelligence could lead to better ways to predict the onset and course of cardiovascular disease. The researchers, working in conjunction with physicians from Intermountain Primary Children's Hospital, developed unique computational tools to precisely measure the synergistic effects of existing medical conditions on the heart and blood vessels. |
Insights into a cystic fibrosis treatment may herald a novel class of drugs Posted: 24 Jan 2022 08:50 AM PST Protein folding diseases, from Alzheimer's to Gaucher's, may one day be treated by a unique class of protein corrector molecules that are already helping manage cystic fibrosis. |
Overweight dogs respond well to high-protein, high-fiber diet Posted: 24 Jan 2022 08:50 AM PST A study of overweight dogs fed a reduced calorie, high-protein, high-fiber diet for 24 weeks found that the dogs' body composition and inflammatory markers changed over time in ways that parallel the positive changes seen in humans on similar diets. The dogs achieved a healthier weight without losing too much muscle mass, and their serum triglycerides, insulin and inflammatory markers all decreased with weight loss. |
Analysis reveals rare disease is more common than previously thought Posted: 24 Jan 2022 08:50 AM PST A large data analysis shows a rare respiratory disease called primary ciliary dyskinesia (PCD) is more common than previously thought. |
How can body weight affect the mortality risk of excessive drinkers? Posted: 24 Jan 2022 08:50 AM PST People with underweight who drink excessively may be at an even higher risk of dying from heart disease, cancer and other causes, according to a new study. |
New software may help neurology patients capture clinical data with their own smartphones Posted: 24 Jan 2022 08:49 AM PST New pose estimation software has the potential to help neurologists and their patients capture important clinical data using simple tools such as smartphones and tablets, according to a new study. |
My heart will go on: Patient-derived heart cells mimic disease in vitro Posted: 24 Jan 2022 07:39 AM PST Researchers have found that induced pluripotent stem cell--derived cardiomyocytes from a patient with arrhythmogenic cardiomyopathy recapitulate the reduced contractility and impaired desmosome assembly associated with this disease, providing a rapid and convenient platform for developing new treatments such as gene replacement therapy. |
Social media use tied to poor physical health Posted: 24 Jan 2022 07:39 AM PST Social media use has been linked to biological and psychological indicators associated with poor physical health among college students, according to new results. Research participants who used social media excessively were found to have higher levels of C-reactive protein (CRP), a biological marker of chronic inflammation that predicts serious illnesses, such as diabetes, certain cancers and cardiovascular disease. In addition to elevated CRP levels, results suggest higher social media use was also related to somatic symptoms, like headaches, chest and back pains, and more frequent visits to doctors and health centers for the treatment of illness. |
Living environment affects child’s weight development from birth to school age Posted: 24 Jan 2022 07:39 AM PST A new study shows that living in asocioeconomic disadvantaged neighborhood is a risk factor for adverse weight development in children under school age. Researchers studied the connection between neighborhoods' socioeconomic status and children's weight development from data covering over 11,000 Finnish children. |
Posted: 24 Jan 2022 07:39 AM PST A newly developed test to screen for three rare genetic disorders simultaneously in newborns was feasible, reliable and scalable, according to a new study. |
Breathing: The master clock of the sleeping brain Posted: 24 Jan 2022 07:38 AM PST Neuroscientists have shown that breathing coordinates neuronal activity throughout the brain during sleep and quiet. |
Landing therapeutic genes safely in the human genome Posted: 24 Jan 2022 06:05 AM PST Researchers have developed a computational approach to identify GSH sites with significantly higher potential for the safe insertion of therapeutic genes and their durable expression across many cell types. For two out of 2,000 predicted GSH sites, the team provided an in-depth validation with adoptive T cell therapies and in vivo gene therapies for skin diseases in mind. By engineering the identified GSH sites to carry a reporter gene in T cells, and a therapeutic gene in skin cells, respectively, they demonstrated safe and long-lasting expression of the newly introduced genes. |
Feelings of fatigue predict early death in older adults Posted: 24 Jan 2022 05:46 AM PST How fatigued certain activities make an older person feel can predict the likelihood death is less than three years away. Researchers show that perceived physical fatigability is an indicator of earlier mortality. |
Men who worry more may develop heart disease and diabetes risk factors at younger ages Posted: 24 Jan 2022 05:46 AM PST In a long-term study of men in the U.S., more high-risk factors for heart disease and Type 2 diabetes developed earlier in life among those who reported more feelings of worry or feeling overwhelmed compared to those with lower levels of worry. The study's results suggest that men prone to worry and anxiety may need to pay extra attention to cardiometabolic disease risk factors, such as maintaining a healthy weight and taking blood pressure or cholesterol medicines, if needed. |
Preoperative shear wave elastography helps predict rotator cuff repair, study finds Posted: 21 Jan 2022 09:47 AM PST Preoperative shear wave elastography (SWE) can play a complementary role with existing imaging as a prognostic marker for achieving successful rotator cuff repair, according to new research. |
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