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| Researchers re-engineer red blood cells to trigger immune system against COVID-19 Posted: 11 Mar 2022 11:14 AM PST Researchers have been able to re-engineer red blood cells and use them as a promising new vehicle for vaccine delivery. |
| Lower, more frequent doses of nanomedicines may enhance cancer treatment Posted: 11 Mar 2022 09:57 AM PST Both nanomedicines and metronomic scheduling -- when medications are given at lower, more frequent doses -- can correct abnormalities surrounding tumors that help protect cancer cells and foster their growth and spread. Combining nanomedicines and metronomic scheduling may help improve cancer treatment strategies. |
| Clinical trial reveals new treatment option for COVID-19 Posted: 11 Mar 2022 08:53 AM PST A clinical trial has indicated an effective treatment for critically ill COVID-19 patients. The study investigates the effects of using an anti-inflammatory protein, alpha-1 antitryspin (AAT), to treat COVID-19 patients who have progressed to acute respiratory distress syndrome (ARDS). |
| Posted: 11 Mar 2022 08:53 AM PST It is well known that methane, a greenhouse gas, is produced by special microorganisms, for example in the intestines of cows, or in rice fields. For some years, scientists had also observed the production of methane in plants and fungi, without finding an explanation. Now researchers have shed light on the underlying mechanism. Their findings suggest that all organisms release methane. |
| Neurons are fickle: Electric fields are more reliable for information Posted: 11 Mar 2022 08:53 AM PST A new study suggests that electric fields may represent information held in working memory, allowing the brain to overcome 'representational drift,' or the inconsistent participation of individual neurons. |
| New window system allows for long-term studies of brain activity Posted: 11 Mar 2022 08:53 AM PST A researcher has developed a tiny window that allows investigators to get clearer, long-term imaging of the brain's visual network. |
| Discovery could lead to fewer side effects from a diabetes treatment Posted: 11 Mar 2022 08:53 AM PST A mouse study detailed the differences between the two forms of the protein PPARgamma, a target of 'glitazone' diabetes drugs, could cut out weight gain side effects. |
| Links between circadian rhythms, metabolism and addiction Posted: 11 Mar 2022 08:53 AM PST A new study establishes important conceptual connections between the fields of circadian rhythms, metabolism, and addiction. Going beyond current studies on substance use disorders, which focus on the impact of addictive drugs on the brain, this new research highlights an existing connection between specific neurons and peripheral organs. |
| Mutations leading to omicron variant did not enable virus to fully escape immune system Posted: 11 Mar 2022 06:53 AM PST People who gained immunity -- either through vaccination or exposure -- against the original strain of SARS-CoV-2, the virus that causes COVID-19, also are likely to have some protection against the pathogen's omicron variant, according to a new study. |
| Exercise may treat long COVID-induced diabetes, depression Posted: 11 Mar 2022 06:53 AM PST While no medically recognized treatment exists for long COVID, exercise may break the vicious cycle of inflammation that can lead to developing diabetes and depression months after a person recovers from the virus. |
| Open-access dataset of macaque brain published Posted: 11 Mar 2022 06:53 AM PST Researchers have published a dataset that was recorded from the visual cortex of monkeys during the resting state. The dataset consists of electrophysiology data that was recorded from the visual cortex (V1 and V4) of two monkeys, from 1024 recording sites simultaneously during the resting state, and it also includes supporting datasets obtained while the monkeys performed visual tasks. |
| Cellular therapy improves signs and symptoms of Duchenne muscular dystrophy Posted: 10 Mar 2022 03:59 PM PST A recent clinical trial has shown that cellular therapy is safe and effective in stopping the deterioration of upper limb and heart functions in patients with late-stage Duchenne muscular dystrophy. |
| Home-based flu tests as accurate as rapid diagnostic testing in clinical settings Posted: 10 Mar 2022 02:08 PM PST Home-based, self-administered tests for influenza are comparable in accuracy to rapid diagnostic tests in clinical settings, according to a peer-reviewed study. The researchers determined that sensitivity and specificity of the home test and clinical test were similar. False-negative results were more common when the self-test was administered after 72 hours of the onset of symptoms, but were not related to inadequate swab collection or severity of illness. |
| Human induced pluripotent stem cells improve visual acuity, vascular health Posted: 10 Mar 2022 02:08 PM PST Researchers are investigating novel regenerative medicine approaches to better manage vascular health complications from type 2 diabetes that could someday support blood vessel repair in the eye among diabetic patients with early retinal vascular dysfunction. |
| Antivirals, some antibodies, work well against BA.2 omicron variant of COVID-19 virus Posted: 10 Mar 2022 02:08 PM PST The antiviral therapies remdesivir, molnupiravir, and the active ingredient in Pfizer's Paxlovid pill (nirmatrelvir), remain effective in laboratory tests against the BA.2 variant of SARS-CoV-2, the virus that causes COVID-19, according to new research. |
| Scientists 'supercharge' cancer-fighting T cells Posted: 10 Mar 2022 02:08 PM PST Scientists have identified a way to 'supercharge' tumor-attacking T cells, a finding that may not only improve the effectiveness of a promising type of cell-based cancer immunotherapy but also expand the number of cancers it can treat. |
| New study confirms bioengineered RSV protein vaccine evokes protective immune response Posted: 10 Mar 2022 02:08 PM PST Researchers marked a major milestone in the effort to create an effective vaccine for respiratory syncytial virus (RSV), which can cause severe respiratory disease in children and the elderly. |
| Gamification, past habits may impact future eco-friendly tendencies differently Posted: 10 Mar 2022 02:08 PM PST Green consumer habits may not be impacted by gamification practices, but people who purchased environmentally friendly products in the past are likely to continue to do so, according to a team of researchers, who theorized that adding gamification techniques to a consumer's eco-friendly purchasing habits would perpetuate green consumerism. |
| Recently discovered protein turbocharges gene expression Posted: 10 Mar 2022 11:37 AM PST Scientists have found intriguing new details about a previously missing critical factor in gene expression. An ancient protein called NDF found in all human tissues enhances gene activation and may be involved in diseases such as cancer. |
| Prenatal mindfulness program improves stress response in infants Posted: 10 Mar 2022 11:37 AM PST Infants whose mothers participated in a mindfulness-based program during pregnancy had healthier stress responses at 6 months old, a new study found. |
| Cancer patients do benefit from COVID-19 vaccination, study finds Posted: 10 Mar 2022 11:37 AM PST A recent study followed 515 patients with varying cancers. The goal was to evaluate if patients had an immune response to the Moderna mRNA-1273 vaccine and if that response differed by diagnosis and treatment. |
| ECMO may offer sickest COVID patients chance for 'exceptional survival', study finds Posted: 10 Mar 2022 11:37 AM PST Some patients with severe COVID-19 who are treated with extracorporeal membrane oxygenation (ECMO) may experience significant lung recovery and return to normal lives with 'meaningful' long-term outcomes, according to research. |
| Damage to inner ear system predicts fall risk among people with Alzheimer's disease Posted: 10 Mar 2022 11:37 AM PST A study of about 50 people with Alzheimer's disease has added to evidence that damage to the inner ear system that controls balance is a major factor in patients' well-documented higher risk of falling. |
| After more than 20 years, scientists have solved the full-length structure of a Janus Kinase Posted: 10 Mar 2022 11:36 AM PST More than two decades of effort went into a project that has now revealed the structure of a crucial signaling molecule, opening the door to new and better drugs for some cancers. |
| How toddler-mother attachment impacts adolescent brain and behavior Posted: 10 Mar 2022 08:51 AM PST Interpersonal trust is a crucial component of healthy relationships. When we interact with strangers, we quickly gauge whether we can trust them. And those important social skills may be shaped by our earliest relationship with caregivers. Adolescents who had an insecure attachment to their mothers as toddlers are more likely to overestimate the trustworthiness of strangers, according to a new study from the University of Illinois. |
| The cellular cleaning program autophagy helps in wound healing Posted: 10 Mar 2022 08:51 AM PST Scientists have shown that the recycling program of cells, autophagy, leads to the fusion of several single cells into multinucleated cell units during wound healing. |
| Blood test as possible diagnostic tool for Alzheimer’s disease Posted: 10 Mar 2022 08:50 AM PST A recent study shows promising results for a blood test that could be used to identify Alzheimer's changes in the brain before the onset of any symptoms, which could result in preventative treatments being used before any memory loss. |
| Could leaky blood vessels in the brain be a culprit in Alzheimer’s disease? Posted: 10 Mar 2022 08:50 AM PST Researchers report that they found high levels of the protein Fli-1 in the brains of deceased Alzheimer's patients. Blocking Fli-1's action in a mouse model of Alzheimer's disease reversed mental loss and reduced the brain inflammation and amyloid-beta clumping that are hallmarks of Alzheimer's disease. Although clinical translation of this finding is likely years off, the study suggests Fli-1 is a promising therapeutic target for Alzheimer's disease. |
| Exploring ancient tuberculosis transmission chains Posted: 10 Mar 2022 08:50 AM PST Tuberculosis (TB) is the second most common cause of death worldwide by an infectious pathogen (after Covid-19), but many aspects of its long history with humans remain controversial. Researchers found that ancient TB discovered in archaeological human remains from South America is most closely related to a variant of TB associated today with seals, but surprisingly these cases were found in people who lived nowhere near the coast. This implies that these cases were not the result of direct transmission from seals, and instead one, or more, spillover events were likely to be the primary drivers of human infection. |
| Rear-end collision on the 'ribosome highway' Posted: 10 Mar 2022 08:50 AM PST As a molecular machine found in the cells of all organisms, the ribosome is responsible for making new proteins. For a number of reasons, this process can fail, leaving the ribosome stalled on the mRNA and bringing synthesis of the protein to a halt. An international research team has now identified a bacterial protein called MutS2 that senses and rescues these stuck protein factories. |
| Seeing lipids more deeply with mass spectrometry Posted: 10 Mar 2022 08:43 AM PST PRMC-MS allows enhanced profiling of phosphoinositide acyl variants both in intracellular and extracellular environments. |
| Robot that seems to convey emotion while reading Posted: 10 Mar 2022 07:00 AM PST Researchers have created a robot with an internal weight that can give the impression of conveying emotions while reading text messages. It can also remind users to not get upset, which may help them cope with unpleasant information. |
| Stealth nanomedicines combat cancer and cut toxic effects of chemo Posted: 10 Mar 2022 07:00 AM PST New research has identified that the frequently used chemotherapy drug (5-FU or Fluorouracil) is 100 per cent more effective at targeting tumors (rather than surrounding tissues) when administered using an optimized liposomal formulation. |
| Eating protein from a greater variety of sources may lower risk of high blood pressure Posted: 10 Mar 2022 06:59 AM PST In a study of nearly 12,200 adults in China, eating protein from a greater variety of sources was associated with a lower risk of developing high blood pressure. This suggests that consuming a balanced diet with a moderate amount of protein from diverse food sources may help prevent new-onset hypertension. |
| Inclusive new tool makes genomic research better reflect world's diversity Posted: 10 Mar 2022 06:59 AM PST Scientists have developed a powerful, inclusive new tool for genomic research that boosts efforts to develop more precise treatments for many diseases by leveraging a better representation of the genetic diversity of people around the world. |
| Treatment length reduced for children with tuberculosis Posted: 09 Mar 2022 03:25 PM PST An international trial exploring the effectiveness of tuberculosis (TB) treatment in children has led to a change in the World Health Organization's global guidelines for managing the disease. |
| Frequent external childcare can affect children's behavior, survey suggests Posted: 09 Mar 2022 11:09 AM PST A survey of around 1,300 Zurich school children, their parents and teachers suggests that the more time children spend in external daycare, the more likely they are to exhibit problematic behavior. However, this behavior generally disappears at the end of primary school. |
| Sleep apnea accelerates aging, but treatment may reverse it Posted: 09 Mar 2022 10:18 AM PST Obstructive sleep apnea (OSA) affects 22 million people in the U.S. and is linked to a higher risk of hypertension, heart attacks, stroke, diabetes and many other chronic conditions. But now researchers have found that untreated OSA also accelerates the biological aging process and that appropriate treatment can slow or possibly reverse the trend. |
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