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| A 'factory reset' for the brain may cure anxiety, drinking behavior, study suggests Posted: 04 May 2022 12:36 PM PDT Gene editing may be a potential treatment for anxiety and alcohol use disorder in adults who were exposed to binge drinking in their adolescence, according to the results of an animal study. The researchers used a gene-editing tool called CRISPR-dCas9 in their experiments to manipulate the histone acetylation and methylation processes at the Arc gene in models of adult rats. |
| Hundreds of injured singers profiled Posted: 04 May 2022 12:12 PM PDT An analysis of more than 400 singers who sought treatment for vocal injuries provides a wealth of data on a topic that's often considered taboo to discuss in the singing community. |
| Scientists engineer new tools to electronically control gene expression Posted: 04 May 2022 11:45 AM PDT Researchers have created an improved method for turning genes on and off using electrical signals. |
| Researchers find link between Parkinson's gene and vocal issues that could lead to earlier diagnosis Posted: 04 May 2022 11:45 AM PDT Neuroscientists found that higher levels of the alpha-synuclein protein in the brain can lead to changes in vocal production. |
| Daily steroids safe and slows progression of duchenne muscular dystrophy, study suggests Posted: 04 May 2022 10:56 AM PDT New research recommends daily steroid doses for children with Duchenne muscular dystrophy, marking a significant change in how the disease is treated. |
| New study reviews anti-cancer activity of sustained release capsaicin formulations Posted: 04 May 2022 10:56 AM PDT A study provides the first published in-depth description of the anti-cancer activity of capsaicin sustained release formulations. Capsaicin is naturally found in chili peppers and is the agent that provides the hot and spicy taste when eating chili peppers. |
| Bye, bye, biopsy? Handheld device could painlessly identify skin cancers Posted: 04 May 2022 10:56 AM PDT A new device uses millimeter-wave imaging -- the same technology used in airport security scanners -- to scan a patient's skin to detect if they have skin cancer. Millimeter-wave rays harmlessly penetrate about 2mm into human skin, so the team's imaging technology provides a clear 3D map of scanned skin lesions. |
| How mosquito brains encode human odor so they can seek us out Posted: 04 May 2022 10:08 AM PDT Some strains of Aedes aegypti -- the mosquito that carries Zika, malaria and dengue fever -- have evolved to bite humans almost exclusively. A team has now discovered how they target us so precisely. |
| Surprising risk factors may predict heart attacks in young women Posted: 04 May 2022 10:08 AM PDT A new study has for the first time identified which risk factors are more likely to trigger a heart attack or acute myocardial infarction (AMI) for men and women 55 years and younger. |
| A healthy lifestyle helps to prevent gestational diabetes in those at highest genetic risk Posted: 04 May 2022 08:04 AM PDT Researchers have developed a genetic-risk score for identifying individuals who would benefit the most from lifestyle counseling to prevent gestational and postpartum diabetes. |
| The role of the cerebellum in absence seizures Posted: 04 May 2022 08:04 AM PDT Researchers have gained new insights into the cellular and molecular mechanisms of absence seizures and potential therapy options. |
| Benefits of exercise may vary greatly in primary mitochondrial disease Posted: 04 May 2022 08:04 AM PDT Researchers demonstrated that the benefits of endurance exercise can vary based on the type of mutation involved in mitochondrial disease, and while the benefits of exercise tend to outweigh the risks, the mitochondrial genetic status of patients should be taken into consideration when recommending exercise as therapy. |
| Gene expression in the nervous system: Mechanism for its targeted stimulation discovered Posted: 04 May 2022 08:04 AM PDT Genes are the carriers of our genetic information. They are read in our cells and used to produce ribonucleic acids (RNAs). During this process, termed transcription, the enzyme RNA polymerase II has a decisive influence on the exact time at which genes are read and on the intensity with which this happens. In their recent article, researchers have shown exactly how RNA polymerase II is activated in nerve cells, and how this stimulates gene expression, the targeted use of genetic information. Their discoveries contain valuable starting points for further biomedical research. |
| New target for CAR T cells in solid tumors Posted: 04 May 2022 08:04 AM PDT Researchers share the identification of a new potential target for CAR T cells called OR2H1 that they have demonstrated inhibits growth in lung and ovarian tumors. |
| Remote programming of cardiac implantable devices is safe for MRI scan, study suggests Posted: 04 May 2022 08:04 AM PDT More than 60 million magnetic resonance imaging (MRI) scans are performed worldwide each year, but imaging for the millions of patients with cardiac implantable electronic devices (CIEDs) such as pacemakers is a logistical challenge, because of concerns with how the magnetic field affects the implants. Now, a newly published study reveals safe and effective reprogramming of these devices is possible, even from a remote location. |
| Researchers manipulate demographic of bacterial community with novel electronic technology Posted: 04 May 2022 08:04 AM PDT Using second-long electrical shocks, scientists discovered they could control the types of cells in a community of bacteria. Being able to direct the ratio of cells holds implications for settings spanning agriculture to health care, where antibiotic resistance is a significant threat. |
| Investigating cancer drug toxicity leads to a critical discovery Posted: 04 May 2022 08:04 AM PDT When patients started showing adverse side effects during a cancer immunotherapy trial, researchers went back through the data and worked with patient samples to see what went wrong. |
| Fungi-based meat alternatives to help save Earth's forests Posted: 04 May 2022 08:04 AM PDT Substituting 20 % of meat from cattle with microbial protein -- a meat alternative produced in fermentation tanks -- by 2050 could halve deforestation, a new analysis finds. The market-ready meat alternative is very similar in taste and texture, but is a biotech product which -- by replacing beef -- involves much less land resources and greenhouse gas emissions from agriculture and land-use change. This goes under the assumption of a growing world population's increasing appetite for beefy bites, and it is the first time researchers have projected the development of these market-ready meat substitutes into the future, assessing their potential impact on the environment. |
| Fecal transplants reverse hallmarks of aging Posted: 04 May 2022 05:26 AM PDT In the search for eternal youth, fecal transplants may seem like an unlikely way to reverse the aging process. However, scientists have provided evidence, from research in mice, that transplanting fecal microbiota from young into old mice can reverse hallmarks of aging in the gut, eyes, and brain. In the reverse experiment, microbes from aged mice induced inflammation in the brain of young recipients and depleted a key protein required for normal vision. These findings show that gut microbes play a role in the regulating some of the detrimental effects of ageing and open up the possibility of gut microbe-based therapies to combat decline in later life. |
| Children's products labeled water- or stain-resistant may contain PFAS Posted: 04 May 2022 05:22 AM PDT Seems like kids are always getting into something, so products marketed toward them often claim to repel liquids. Some items contain potentially harmful per- and polyfluoroalkyl substances (PFAS) to accomplish this feat, but companies aren't required to disclose these 'forever chemicals' on labels. Now, researchers show that some children's products advertised as water- or stain-resistant contain PFAS, even items labeled 'green' or 'nontoxic.' |
| Mental illness plays havoc with the mind as well as the heart Posted: 03 May 2022 05:16 PM PDT We need to pay more attention to the physical impacts of mental illness. It could not only be messing with your mind, but also your heart, say scientists. |
| Brain circuit responsible for cocaine withdrawal-induced anxiety and relapse-related behavior Posted: 03 May 2022 04:02 PM PDT New research finds that drug withdrawal-induced anxiety and reinstatement of drug seeking behaviors are controlled by a single pathway in the brain and centered around dopamine cells. |
| How alcohol cravings get stronger after drinking during withdrawal Posted: 03 May 2022 04:02 PM PDT A new finding in an animal study could eventually lead to improved treatments to minimize cravings in people with alcohol use disorder. |
| Diet type can increase potentially harmful gas in the gut Posted: 03 May 2022 04:02 PM PDT Scientists looked at colonic hydrogen sulfide -- a toxic gas in the body that smells like rotten eggs -- production in people in response to animal- and plant-based diet interventions. |
| B12 deficiency harms young children's development, and the food relief we provide isn't good enough Posted: 03 May 2022 11:13 AM PDT Vitamin B12 deficiency in infants leads to poor motor development and anemia, according to a new study . B12 deficiency is an enormous, yet overlooked problem, and the food relief currently suppied is not helping. According to the researchers, the problem calls for new solutions. |
| Student satisfaction in flipped classroom is built on guidance, pedagogy, and a safe atmosphere Posted: 03 May 2022 11:13 AM PDT Students are satisfied with flipped classroom when they have systematic guidance on the teaching approach in use, comprehensive understanding of both the content being taught and the discipline more generally, and a safe learning atmosphere conducive to conversation. Teachers also need to pay attention to the students' technological skills and their own contact teaching skills, according to a new study. |
| Posted: 03 May 2022 11:13 AM PDT During experiments in animal models, researchers have discovered a possible new approach to immunization against Alzheimer's disease. Their method uses a recombinant methionine (Met)-rich protein derived from corn that was then oxidized in vitro to produce the antigen: methionine sulfoxide (MetO)-rich protein. |
| Brain networks can play role in weight-loss success Posted: 03 May 2022 11:13 AM PDT When it comes to weight loss, the old adage it's all in your head may be true. Scientists have shown that two specific networks in the brain can strongly influence how successful a person will be when trying to lose weight. |
| For stroke survivors, modified cardiac rehabilitation can reduce the chances of death by 76% Posted: 03 May 2022 11:13 AM PDT Survivors of serious stroke can reduce their chances of dying within the year by 76% if they complete a modified cardiac rehabilitation program that includes medically supervised exercise, prescribed therapy, and physician follow-up, according to new research. The findings have the potential to change the future of stroke care. |
| Dog coronavirus jumps to humans, with a protein shift Posted: 03 May 2022 11:13 AM PDT Researchers have identified a shift that occurs in canine coronavirus that may provide clues as to how it transmits from animals to humans. |
| Finding your car in a parking lot relies on this newly discovered brain circuit Posted: 03 May 2022 11:13 AM PDT When exploring a new environment, mice make use of a unique long-distance connection in the brain that prompts them to pay attention to the most salient features of the environment, according to new research. The link, originating in the prefrontal cortex and stretching to the hippocampus, provides evidence of how the brain's higher cognitive regions refine operations occurring in distant brain areas. |
| Combination of drugs for obesity and Type 2 diabetes may be more effective than a single therapy Posted: 03 May 2022 11:13 AM PDT Researchers have identified new drug combinations to treat people with obesity and Type 2 diabetes. The goal is to develop personalized prescriptions that are more effective than single drugs and that can potentially replace more invasive treatments such as bariatric surgery, especially for children. |
| Acute sleep loss may alter the way we see others Posted: 03 May 2022 07:29 AM PDT A new study shows that young adults when sleep-deprived evaluate angry faces as less trustworthy and healthy-looking. Furthermore, neutral and fearful faces appear less attractive following sleep loss. |
| Emphysema severity associated with higher lung cancer risk Posted: 03 May 2022 07:28 AM PDT CT-detected emphysema is linked to a higher risk of lung cancer, a risk that increases with emphysema severity, according to a new study. |
| Student debt can impair your cardiovascular health into middle age, study finds Posted: 03 May 2022 05:31 AM PDT Individuals with student loan debt into early middle age have a higher risk of cardiovascular illness, undermining the usual health benefits of a post-secondary education, researchers report. |
| Cognitive impairment from severe COVID-19 equivalent to 20 years of aging, study finds Posted: 03 May 2022 05:31 AM PDT Cognitive impairment as a result of severe COVID-19 is similar to that sustained between 50 and 70 years of age and is the equivalent to losing 10 IQ points, say scientists. |
| Want more students to learn languages? Win over the parents, research suggests Posted: 02 May 2022 04:47 PM PDT New research shows that children's willingness to study subjects like French, German or Spanish is shaped far more by the attitudes of their parents, than by their teachers or friends. The study's authors argue that efforts to reverse the steady decline in language-learning in the UK should target families rather than just children, because of the important role parents' beliefs play in shaping children's views of themselves as language-learners. |
| Gene therapy reverses effects of autism-linked mutation in brain organoids Posted: 02 May 2022 09:54 AM PDT Scientists use lab-grown human brain tissue to identify neural abnormalities in Pitt-Hopkins Syndrome and show gene therapy tools can rescue neural structure and function. |
| Sensor makes strides in detecting infection indicators Posted: 02 May 2022 09:04 AM PDT Bioengineers have designed a wearable sensor that can detect two key biomarkers of infection in human sweat, a significant step toward making it possible for users to receive early warnings of infections such as COVID-19 and influenza. |
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