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New way of generating insulin-producing cells Posted: 13 Jun 2022 11:07 AM PDT Researchers show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis. |
Biochemists use enzymes to change how brain cells communicate with each other Posted: 13 Jun 2022 11:07 AM PDT A new study demonstrates the possibility of changing the identity of synapses between neurons, both in vitro and in vivo, through enzymatic means. The results have implications for treating brain diseases caused by malfunctions in synaptic information processing and exchange. |
RNA exosome key for B cell development Posted: 13 Jun 2022 11:07 AM PDT New research suggests that RNA exosomes -- the cellular machines that degrade old molecules of RNA -- play a key role in the development of B cells, which are critical to the immune system's ability to protect against infection. The findings explain why patients with rare mutations in a gene that codes for this machinery are often immunodeficient and could offer new approaches to treat autoimmune diseases. |
Pediatric liver disease increases risk of developing type 2 diabetes Posted: 13 Jun 2022 11:07 AM PDT Researchers describe connection between pediatric liver disease and increased risk of developing type 2 diabetes. Both rates are rising in children. |
Increased overdose and mental health risks persist two years after opioid dose reduction Posted: 13 Jun 2022 09:45 AM PDT A new study suggests that the increased rates of overdose and mental health crisis observed during the first year after opioid dose tapering persist through the second year. |
Estimating tumor-specific total mRNA level predicts cancer outcomes Posted: 13 Jun 2022 09:45 AM PDT Researchers have developed a mathematical tool to estimate tumor-specific RNA levels from tumor samples with mixed cell types. Using this technique on thousands of samples found that higher mRNA levels are correlated with shorter survival. |
Molecule in the nervous system may hold key to treating chronic pain Posted: 13 Jun 2022 08:21 AM PDT Researchers reveal a potential new way to treat chronic pain using anti-cancer drugs rather than opioid-based pain medication. Researchers identified the existence of a molecule in the nervous system that enhances sensitivity to pain. This molecule had previously been thought to play a role in cancer growth but had never been reported in the nervous system. By targeting this molecule it may now be possible to use already existing anti-cancer drugs to block pain. |
Study shows people 'right size' portions of high-calorie foods Posted: 13 Jun 2022 08:21 AM PDT New research has revealed that humans moderate the size of energy-rich meals they eat, suggesting people are smarter eaters than previously thought. |
Healthy human brains are hotter than previously thought, research finds Posted: 13 Jun 2022 08:21 AM PDT New research has shown that normal human brain temperature varies much more than we thought, and this could be a sign of healthy brain function. The new study has produced the first 4D map of healthy human brain temperature. This map overturns several previous assumptions and shows the remarkable extent to which brain temperature varies by brain region, age, sex, and time of day. |
Brain differences in pain modulation in people with self-injury behavior Posted: 13 Jun 2022 08:21 AM PDT Researchers might have found an explanation for why people with self-injury behavior generally feel less pain than others. The key seems to be a more effective pain-modulation system, a discovery that can benefit people seeking help for their self-harm. |
'Merlin' serves as a gatekeeper in new blood vessel formation Posted: 13 Jun 2022 08:21 AM PDT 'Merlin' serves as a gatekeeper in new blood vessel formation. Merlin suppresses internalization of VEGFR2, which is important for the formation of 'tip' endothelial cells. |
Forever chemicals linked to hypertension in middle-aged women Posted: 13 Jun 2022 08:21 AM PDT In a large, prospective study, the levels of per- and polyfluoroalkyl substances (PFAS), which are common human-made chemicals found in water, soil, air and food, were associated with an increased risk of high blood pressure among middle-aged women. The study found women in the highest one-third concentrations of all seven PFAS examined had a 71% increased risk of developing high blood pressure. |
Older adults more likely to have multiple health ailments than prior generations Posted: 13 Jun 2022 08:19 AM PDT Later-born generations of older adults in the United States are more likely to have a greater number of chronic health conditions than the generations that preceded them, according to a new study. |
Bacterial intimacy insights could help tackle antimicrobial resistance Posted: 13 Jun 2022 08:19 AM PDT Researchers have uncovered new details about how bacteria hook up to exchange DNA that helps them resist antibiotics. |
Good news on blocking a virus considered a global threat Posted: 13 Jun 2022 08:15 AM PDT Scientists have reported good news on the pandemic preparedness front: A cocktail of four manufactured antibodies is effective at neutralizing a virus from the Henipavirus family, a group of pathogens considered to be a global biosecurity threat. |
Children in remote school faced more sleep, behavior and social challenges Posted: 13 Jun 2022 08:15 AM PDT Elementary school-aged children enrolled in remote learning experienced greater behavioral, learning-related, and sleep difficulties compared with children receiving in-person instruction, according to the findings of a new study. |
Are we born with a moral compass? Posted: 09 Jun 2022 10:19 AM PDT Researchers found that preverbal infants can make and act on moral judgments about antisocial behavior in a third party. Using a new cognitive paradigm with gaze tracking, researchers were able to show that 8-month-old infants can engage in third-party punishment. This indicates that humans may have acquired morality through evolution, and opens the door for future experiments to investigate unexplored elements of infant cognition. |
Investigators discover a 'double life' for a key Parkinson's disease protein Posted: 09 Jun 2022 10:00 AM PDT One of the hallmarks of Parkinson's disease (PD) is the accumulation in the brain of a protein known as alpha-synuclein. A new study shines new light on the role of alpha-synuclein, uncovering a new function for the protein with relevance for PD and related conditions. The team's findings are published in Cell. |
New CDC study details county-level distribution of seven diseases spread by blacklegged ticks Posted: 08 Jun 2022 03:44 PM PDT As surveillance for ticks and the disease-causing germs they spread improves, so does Americans' access to knowledge about where the risk of tickborne disease is greatest. Experts have assembled new surveillance data into a report that offers up-to-date county-level maps of both where blacklegged ticks are prevalent and where they've been found infected with any of seven different disease-causing germs, or pathogens. |
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