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Fast, efficient COVID-19 biosensor under development Posted: 21 Jul 2022 11:15 AM PDT Researchers are developing a 'biosensing platform' for COVID-19 that's fast, efficient, accurate and highly sensitive, which could help scientists stay on top of shifting virus variants. |
Taste sensors keep proteins in order in flies Posted: 21 Jul 2022 11:15 AM PDT A set of genes that promote sweet taste sensation is also crucial for protein management during fly development, according to a new study. The finding expands the understanding of a key process in successful development, and suggests a connection between taste-related genes and disorders of protein aggregation. |
A novel COVID-19 vaccine using modified bacterial DNA Posted: 21 Jul 2022 11:14 AM PDT Researchers describe a different way to build a COVID-19 vaccine, one that would, in theory, remain effective against new and emerging variants and could be taken as a pill, by inhalation or other delivery methods. |
Medical face mask membrane that can capture, deactivate SARS-CoV-2 spike protein on contact Posted: 21 Jul 2022 10:20 AM PDT SARS-CoV-2 is covered in spike proteins, which allow the virus to enter host cells once in the body. Researchers have developed a membrane that includes proteolytic enzymes that attach to the protein spikes and deactivate them. |
Cancer cells make unique form of collagen, protecting them from immune response Posted: 21 Jul 2022 10:20 AM PDT Cancer cells produce small amounts of their own form of collagen, creating a unique extracellular matrix that affects the tumor microbiome and protects against immune responses. This abnormal collagen structure is fundamentally different from normal collagen made in the human body, providing a highly specific target for therapeutic strategies. |
Posted: 21 Jul 2022 10:20 AM PDT Macrophages play a central role in our immune response. They can trap and digest invading pathogens. However, specific bacteria such as Salmonella or Mycobacteria can survive the digestive system of macrophages and escape the control of immune cells. Research reveals how different organelle systems communicate to activate a more effective anti-bacterial defense mechanism. Successful elimination of specific bacteria in the phago-lysosomal system depends on a signal controlling mitochondria. The yet unknown phago-lysosome-mitochondria crosstalk in macrophages leads to a better understanding of how immune cells work and may identify new intervention points for treating infectious diseases. |
Blockchain gives Indigenous Americans control over their genomic data Posted: 21 Jul 2022 10:19 AM PDT Despite existing tools that facilitate the sharing of genomic information with researchers, none of those options give Indigenous governments control over how these data are used. In a new article, authors propose a new blockchain model where researchers are only allowed to access the genomic data after the Indigenous entities have approved the research project. |
Patient deterioration predictor could surpass limits of traditional vital signs Posted: 21 Jul 2022 10:19 AM PDT A device driven by artificial intelligence that works to predict when a patient will deteriorate could provide a more accurate picture than traditional vital signs, a new study suggests. The technology continuously monitors patients using data from a single electrocardiogram lead, and researchers say it has the potential to save lives anywhere from the hospital to the battlefield. |
Pharmacist-based deprescribing successfully reduced older adults' exposure to anticholinergic drugs Posted: 21 Jul 2022 07:15 AM PDT A new study has found that using pharmacists as deprescribing care coordinators decreased prescription of anticholinergics by 73 percent and reduced cumulative use of these drugs by as much as 70 percent. |
North 'plaza' in Cahokia was likely inundated year-round Posted: 21 Jul 2022 07:15 AM PDT The ancient North American city of Cahokia had as its focal point a feature now known as Monks Mound, a giant earthwork surrounded on its north, south, east and west by large rectangular open areas. A new study of the north plaza suggest it was almost always underwater, calling into question earlier interpretations of the north plaza's role in Cahokian society. |
Posted: 21 Jul 2022 07:15 AM PDT Lighting up the B cells. Distinguishing B cells from T cells using an SLC35C2 transporter-targeting fluorescent probe. |
Protective T cells remain 20 months after COVID-19, study finds Posted: 21 Jul 2022 07:15 AM PDT Highly specialized T cells are detectable in blood for at least 20 months after SARS-cov-2 infection, a new study shows. |
How vaccine-related fears affect the flu shot experience Posted: 21 Jul 2022 07:14 AM PDT A novel long-term study of how vaccine-related fears influence flu shot outcomes has found that these fears not only reduce vaccination, but also fuel symptoms of dizziness and lightheadedness at the time of the injection. |
Finding the right target to prevent medulloblastoma relapse Posted: 20 Jul 2022 04:37 PM PDT Using a GLI inhibitor, rather than a SMO inhibitor, made medulloblastoma tumors smaller and weaker. |
Do benefits of physical, mental activity on thinking differ for men and women? Posted: 20 Jul 2022 04:37 PM PDT Studies have shown that physical and mental activity help preserve thinking skills and delay dementia. A new study suggests that these benefits may vary for men and women. |
Post-COVID lung disease shares origins with other scarring lung disorders Posted: 20 Jul 2022 04:37 PM PDT Researchers provide first insights into the fundamental cellular pathologies that drive interstitial lung disease in patients post-COVID. |
Novel gene therapy could reduce bleeding risk for haemophilia patients Posted: 20 Jul 2022 04:37 PM PDT A single gene therapy injection could dramatically reduce the bleeding risk faced by people with haemophilia B, finds a new study. |
Hypertension elevates risk for more severe COVID-19 illness Posted: 20 Jul 2022 04:37 PM PDT Hypertension more than doubles the risk of hospitalization related to Omicron infection, even in people who are fully vaccinated and boosted, according to a new study. |
Overconfidence bolsters anti-scientific views, study finds Posted: 20 Jul 2022 04:37 PM PDT Historically, the scientific community has relied on educating the public in order to increase agreement with scientific consensus. New research suggests why this approach has seen only mixed results. |
Cellular protein identified as possible drug target to combat Lassa hemorrhagic fever Posted: 20 Jul 2022 12:06 PM PDT Experimental approach could uncover new treatment options for the virus, which is highly prevalent in Western Africa. |
Engineered mattress tricks your body to fall asleep faster Posted: 20 Jul 2022 12:06 PM PDT Bioengineers have developed a unique mattress and pillow system that uses heating and cooling to tell the body it is time to go to sleep. |
Putting the brakes on 'budding' viruses Posted: 20 Jul 2022 12:06 PM PDT Paramyxoviruses have the potential to trigger a devastating pandemic. This family of viruses includes measles, Nipah virus, mumps, Newcastle disease and canine distemper. An international team has examined key stage in the life cycles of measles and Nipah viruses. It reveals how future therapies might stop these viruses in their tracks. |
Higher rates of preterm birth in women infected with COVID-19 in late pregnancy Posted: 20 Jul 2022 12:06 PM PDT SARS-CoV-2 infection is associated with an increased risk of preterm birth, but only for women infected in their final trimester, according to researchers. The study of over 5,000 pregnant women is one of the first to look at pregnancy outcomes for COVID-19 patients by trimester. |
Psychological traits of violent extremism investigated using new research tool Posted: 20 Jul 2022 12:06 PM PDT Researchers have developed and validated a new tool known as the Extremist Archetypes Scale to help distinguish different psychological traits found among people engaged in violent extremism. |
Beliefs in conspiracy theories may not be increasing Posted: 20 Jul 2022 12:06 PM PDT A new analysis contradicts popular thinking about beliefs in conspiracy theories, suggesting that such beliefs may not have actually increased over time. |
Alexa and Siri, listen up! Teaching machines to really hear us Posted: 20 Jul 2022 12:05 PM PDT The implications of new AI voice research go beyond user experience to making AI more efficient, which could change the industry and significantly reduce carbon footprints. |
Study details U.S. health spending by region Posted: 20 Jul 2022 12:05 PM PDT A new study provides the first nationwide, small-area analysis of the variation in spending by the three main funders of health care in the United States: Medicare, Medicaid, and private insurers. The researchers' goal: to see whether there are regions that have low health spending by each of the three payers simultaneously or whether distinct factors drive health spending variation among the payers. |
Study shows widespread mislabeling of CBD content occurs for over-the-counter products Posted: 20 Jul 2022 09:10 AM PDT Researchers tested more than 100 topical cannabidiol (CBD) products available online and at retail stores, and found significant evidence of inaccurate and misleading labeling of CBD content. |
Surgery risks go up depending upon the anesthesiologist's workload, study suggests Posted: 20 Jul 2022 09:10 AM PDT A new study examines whether the number of overlapping procedures managed by the anesthesiologist increases the risk of death or complications after surgery. |
New fast test discriminates between cellular immunity to SARS-CoV-2 after vaccination or infection Posted: 20 Jul 2022 07:25 AM PDT Researchers have developed a new blood test that indicates a person's status of cellular immunity to SARS-CoV-2 within just 48 hours. This test is particularly relevant for vulnerable patient groups, whose own antibody response is not meaningful. The test can even indicate whether immunity is the result of vaccination against SARS-CoV-2 or of survived infection. |
Scientists develop a new non-opioid pain killer with fewer side effects Posted: 20 Jul 2022 07:25 AM PDT Scientists have investigated a compound called BnOCPA (benzyloxy-cyclopentyladenosine), found to be a potent and selective analgesic which is non-addictive in test model systems. BnOCPA also has a unique mode of action and potentially opens a new pipeline for the development of new analgesic drugs. |
Posted: 20 Jul 2022 05:01 AM PDT Researchers found that analyzing short amino acid segments from T-cells could improve machine learning algorithms that predict the infection history of the donor. Based on the performance comparison using multiple diseases and sample size, the resulting algorithm could outperform existing solutions on smaller datasets. This work may enable a wider range of rare diseases to be diagnosed by future immunological blood testing. |
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