Metabolic measurement of humans and animal models is an important aspect of biomedicine. However, the limitations of current methods in metabolic measurement are not widely understood. This mini-review explains the methodological trade-offs involved in metabolic measurement with flow-through respirometry and specifically addresses limitations regarding temporal resolution and accuracy of metabolic measurement systems with practical solutions.

Brazilian scientists have performed early preclinical studies that suggest a low dose of the antibiotic doxycycline may offer a potential treatment against Parkinson's disease by reducing the toxicity of the protein alpha-synuclein.

Researchers have developed a new crawling assay using mutated fruit fly larvae and an open-source application called LarvaTrack that they say provide a quick, reproducible and cost-effective way of uncovering potential treatments for fragile X syndrome.

Due to an increase in the abuse of synthetic insulins, doping laboratories require faster and more consistent testing options. The methodology to detect and confirm the presence of peptide hormones by mass spectrometry is preferred to the current use of immunoassays or other immuno-reactive techniques. This white paper explores and compares the different available methods, revealing the fastest and most accurate options for synthetic insulin detection.

A novel hydrogel antibacterial wound covering could help in the fight against antimicrobial resistance by preventing thousands of people each year from developing infections.

A potential cure for Type 1 diabetes looms on the horizon in San Antonio, and the novel approach would also allow Type 2 diabetics to stop insulin shots.

The mechanisms that activate special stem cells or make them go back to sleep after their work is done have remained elusive until now. The scientists have now identified retinoic acid, a vitamin A metabolite, as a crucial factor in this process.

A new study has revealed two key findings for people with irritable bowel syndrome about the relationship between the microorganisms that live in the gut and the brain.

Much is known about flu viruses, but little is understood about how they reproduce inside human host cells, spreading infection. Now, a research team is the first to identify a mechanism by which influenza A hijacks cellular machinery to replicate.

Vladimir Lukhtanov, entomologist and evolutionary biologist, made a startling discovery: what people had thought was a population of a common species, turned out to be a whole new organism and, moreover - one with an interesting evolutionary history.