Updates to the Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV

The Panel on Opportunistic Infections in Adults and Adolescents (the Panel) updated the Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV. Highlights from the updated section are summarized below: 

Bacterial Enteric Infections

• Updated information on the management and treatment of Clostridioides difficile (C. difficile) disease now aligned with the recent Infectious Diseases Society of America guidelines.
• Expanded discussion of the role of fidaxomicin and bezlotoxumab in the therapy of C. difficile disease.

For a list of recent updates, please see What's New in the Guidelines. To view or download the guidelines, go to the Adult and Adolescent Opportunistic Infection Guidelines section of Clinical Info’s website. The guidelines tables and recommendations also can be downloaded as separate PDF files. 

Clinical Info Welcomes Your Feedback on the latest revisions to Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV.  Please send your comments with the subject line “Adult and Adolescent Opportunistic Infection Guidelines” to Contact-HIVinfo@NIH.gov by May 3, 2022.